• Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Leu24-Thr495
Catalog #MUK-CM101
Price
Regular price $37950
Regular price Sale price $37950
/
Size
Avantor VWR Fisher Scientific

Order by 4pm ET for delivery on:

Cynomolgus Musk (muscle, skeletal receptor tyrosine-protein kinase) Protein (MUK-CM101) Summary

Product Description

 Recombinant Cynomolgus Musk (muscle, skeletal receptor tyrosine-protein kinase) Protein is expressed from HEK293 with His tag at the C-terminus.It contains Leu24-Thr495.

Product Background

 MuSK (muscle-specific kinase) is a receptor tyrosine kinase that plays a central signaling role in the formation of neuromuscular junctions (NMJs). MuSK is activated in a complex spatio-temporal manner to cluster acetylcholine receptors on the postsynaptic (muscle) side of the synapse and to induce differentiation of the nerve terminal on the presynaptic side.

Cynomolgus Musk (muscle, skeletal receptor tyrosine-protein kinase) Protein (MUK-CM101) Specifications/Details

Protein
 Musk (muscle, skeletal receptor tyrosine-protein kinase)
Synonyms
 EC:2.7.10.1; MuSK; Muscle-specific kinase receptor
Accession
Species
 Cynomolgus
Biotinylated
 no
Amino Acid Range
 Leu24-Thr495
Molecular Weight
 The protein has a predicted MW of 53.40 kDa. Due to glycosylation, the protein migrates to 65-75 kDa based on Bis-Tris PAGE result.
Product Tag
 C-His
Fluorophore
 Unconjugated
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
 -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Cynomolgus Musk (muscle, skeletal receptor tyrosine-protein kinase) on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Cynomolgus Musk (muscle, skeletal receptor tyrosine-protein kinase) on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Cynomolgus Musk (muscle, skeletal receptor tyrosine-protein kinase) is greater than 95% as determined by SEC-HPLC. The purity of Cynomolgus Musk (muscle, skeletal receptor tyrosine-protein kinase) is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...