Cynomolgus NKp46/NCR1/CD335 Protein (NKP-CM246)
Cynomolgus NKp46/NCR1/CD335 Protein (NKP-CM246)
Cynomolgus NKp46/NCR1/CD335 Protein (NKP-CM246)
Cynomolgus NKp46/NCR1/CD335 Protein (NKP-CM246)
  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Cynomolgus NKp46, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-Nkp46 Antibody, hFc Tag with the EC50 of 18.9ng/ml determined by ELISA (QC Test). See testing image for detail.
  • Amino Acid Range: Pro22-Asn254
Catalog #NKP-CM246
Regular price $346.50
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Cynomolgus NKp46/NCR1/CD335 Protein (NKP-CM246) Summary

Product Description

Recombinant Cynomolgus NKp46/NCR1/CD335 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Pro22-Asn254.

Product Background

NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expressed almost exclusively by NK cells and play a major role in triggering some of the key lytic activities of NK cells.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others

Cynomolgus NKp46/NCR1/CD335 Protein (NKP-CM246) Specifications/Details

Protein
NKp46/NCR1/CD335
Synonyms
CD335; Ly94; NCR1; NKp46; MAR-1; NKP46FLJ99094
Accession
Species
Cynomolgus
Biotinylated
no
Amino Acid Range
Pro22-Asn254
Molecular Weight
The protein has a predicted MW of 53.1 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Activity
Immobilized Cynomolgus NKp46, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-Nkp46 Antibody, hFc Tag with the EC50 of 18.9ng/ml determined by ELISA (QC Test). See testing image for detail.

Product Tag

C-hFc
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Cynomolgus NKp46, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-Nkp46 Antibody, hFc Tag with the EC50 of 18.9ng/ml determined by ELISA (QC Test). Immobilized Cynomolgus NKp46, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-Nkp46 Antibody, hFc Tag with the EC50 of 18.9ng/ml determined by ELISA (QC Test).
Cynomolgus NKp46 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Cynomolgus NKp46 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Cynomolgus NKp46 is greater than 95% as determined by SEC-HPLC. The purity of Cynomolgus NKp46 is greater than 95% as determined by SEC-HPLC.
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