Cynomolgus NOGOR Protein (NOG-CM101)
Catalog: NOG-CM101
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Product Description | Recombinant Cynomolgus NOGOR Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Cys27-Ser447. |
Product Background |
NOGO Receptor 1 (RTN4R) regulates axonal growth, as well as axon regeneration after injury. The gene maps to the 22q11.2 schizophrenia susceptibility locus and is thus a strong functional and positional candidate gene.RTN4R may modulate the genetic risk or clinical expression of schizophrenia in a subset of patients and identify additional studies that will be necessary to clarify the role of RTN4R in psychiatric phenotypes. |
Product Category |
Recombinant Protein |
Target |
NOGOR |
Accession | |
Species |
Cynomolgus |
Amino Acid Range |
Cys27-Ser447 |
Molecular Weight | The protein has a predicted MW of 46.34 kDa. Due to glycosylation, the protein migrates to 60-73 kDa based on Tris-Bis PAGE result. |
Activity |
Immobilized Cynomolgus NOGOR, His Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Anti-NOGOR Antibody, hFc Tag with the EC50 of 18.0ng/ml determined by ELISA. See testing image for detail. |
Product Tag |
C-His |
Express System |
HEK293 |
Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
Endotoxin | Less than 1EU per ug by the LAL method. |
Form | Lyophilized |
Shipping | Shipped at ambient temperature. |
Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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