Cynomolgus NOGOR Protein (NOG-CM101)

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Activity: Immobilized Cynomolgus NOGOR, His Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Anti-NOGOR Antibody, hFc Tag with the EC50 of 18.0ng/ml determined by ELISA. See testing image for detail.
Exact Sequence: Cys27-Ser447

Catalog: NOG-CM101

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Product Description	Recombinant Cynomolgus NOGOR Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Cys27-Ser447.
Product Background	NOGO Receptor 1 (RTN4R) regulates axonal growth, as well as axon regeneration after injury. The gene maps to the 22q11.2 schizophrenia susceptibility locus and is thus a strong functional and positional candidate gene.RTN4R may modulate the genetic risk or clinical expression of schizophrenia in a subset of patients and identify additional studies that will be necessary to clarify the role of RTN4R in psychiatric phenotypes.
Product Category	Recombinant Protein

Target	NOGOR
Gene/Protein ID	Q9N0E3
Species	Cynomolgus
Exact Sequence	Cys27-Ser447
Molecular Weight	The protein has a predicted MW of 46.34 kDa. Due to glycosylation, the protein migrates to 60-73 kDa based on Tris-Bis PAGE result.
Activity	Immobilized Cynomolgus NOGOR, His Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Anti-NOGOR Antibody, hFc Tag with the EC50 of 18.0ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-His
Express System	HEK293
Purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Immobilized Cynomolgus NOGOR, His Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Anti-NOGOR Antibody, hFc Tag with the EC50 of 18.0ng/ml determined by ELISA.
	The purity of Cynomolgus NOGOR is greater than 95% as determined by SEC-HPLC.
	Cynomolgus NOGOR on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.