Cynomolgus NPR1/NPRA Protein (NPR-CM101)
Cynomolgus NPR1/NPRA Protein (NPR-CM101)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Gly33-Glu473
Catalog #NPR-CM101
Regular price $345.00
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Product Description

Recombinant Cynomolgus NPR1/NPRA Protein is expressed from HEK293 with His tag at the C-terminus.It contains Gly33-Glu473.

Product Background

NPR1 (natriuretic peptide receptor 1), a receptor of ANP (atrial natriuretic peptide) whitch acting through NPR1, provokes hypotension. NPR1 was abundantly expressed in endothelial cells and smooth muscle cells of small arteries and arterioles. NPR1 plays a crucial role in ANP-mediated blood pressure regulation, presumably by a mechanism that is RGS2-dependent in the acute phase and RGS2-independent in the chronic phase.

Product Category

Recombinant Protein / Antibody discovery

Protein

NPR1/NPRA

Synonyms

ANP-A; ANPR-A; NPR-A; GC-A; ANPRA

Accession

Species

Cynomolgus

Biotinylated

no

Amino Acid Range

Gly33-Glu473

Molecular Weight

The protein has a predicted MW of 50.50 kDa. Due to glycosylation, the protein migrates to 60-80 kDa based on Bis-Tris PAGE result.

Product Tag

C-His

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Cynomolgus NPR1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Cynomolgus NPR1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Cynomolgus NPR1 is greater than 95% as determined by SEC-HPLC. The purity of Cynomolgus NPR1 is greater than 95% as determined by SEC-HPLC.

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