Cynomolgus NPR1/NPRA Protein (NPR-CM301)
Cynomolgus NPR1/NPRA Protein (NPR-CM301)
  • Express System: HEK293
  • Product Tag: C-mFc
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Gly33-Glu473
Catalog #NPR-CM301
Regular price $345.00
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Product Description
Recombinant Cynomolgus NPR1/NPRA Protein is expressed from HEK293 with mFc (IgG1) tag at the C-terminus.It contains Gly33-Glu473.
Product Background
NPR1 (natriuretic peptide receptor 1), a receptor of ANP (atrial natriuretic peptide) whitch acting through NPR1, provokes hypotension. NPR1 was abundantly expressed in endothelial cells and smooth muscle cells of small arteries and arterioles. NPR1 plays a crucial role in ANP-mediated blood pressure regulation, presumably by a mechanism that is RGS2-dependent in the acute phase and RGS2-independent in the chronic phase.
Product Category
Recombinant Protein
Target
NPR1/NPRA
Synonyms
ANP-A; ANPR-A; NPR-A; GC-A; ANPRA
Accession
Species
Cynomolgus
Biotinylated
no
Amino Acid Range
Gly33-Glu473
Molecular Weight
The protein has a predicted MW of 74.56 kDa. Due to glycosylation, the protein migrates to 80-110 kDa based on Bis-Tris PAGE result.
Product Tag
C-mFc
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Cynomolgus NPR1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Cynomolgus NPR1 is greater than 95% as determined by SEC-HPLC.

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