Name: Cynomolgus OSMR Protein (OSM-CM101)
Brand: KactusBio
SKU: OSM-CM101-100UG
Price: 346.5 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Cynomolgus OSMR, His Tag at 2 ug/ml (100 ul/well) on the plate. Dose response curve for Anti-OSMR Antibody, hFc Tag with the EC50 of 8.4 ng/ml determined by ELISA.
Amino Acid Range: Glu28-Ser737

Catalog #OSM-CM101

Size

100UG

500UG

Order by 4pm ET for delivery on:

Cynomolgus OSMR Protein (OSM-CM101) Summary

Product Description	Recombinant Cynomolgus OSMR Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu28-Ser737.
Product Background	OSMR is targeted to the mitochondrial matrix via the presequence translocase-associated motor complex components, mtHSP70 and TIM44. OSMR interacts with NADH ubiquinone oxidoreductase 1/2 (NDUFS1/2) of complex I and promotes mitochondrial respiration. Deletion of OSMR impairs spare respiratory capacity, increases reactive oxygen species, and sensitizes BTSCs to IR-induced cell death.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Cynomolgus OSMR Protein (OSM-CM101) Specifications/Details

Protein	OSMR
Synonyms	IL-31R subunit beta; IL-31R-beta; IL-31RB; OSMR beta; OSMR; OSMRB; OSMRBMGC150626; PLCA1 ;IL-31R subunit β; IL-31R-β; OSMR β
Accession	A0A2K5UFW5
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Glu28-Ser737
Molecular Weight	The protein has a predicted MW of 82.04 kDa. Due to glycosylation, the protein migrates to 110-130 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Cynomolgus OSMR, His Tag at 2 ug/ml (100 ul/well) on the plate. Dose response curve for Anti-OSMR Antibody, hFc Tag with the EC50 of 8.4 ng/ml determined by ELISA.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Cynomolgus OSMR, His Tag at 2 ug/ml (100 ul/well) on the plate. Dose response curve for Anti-OSMR Antibody, hFc Tag with the EC50 of 8.4 ng/ml determined by ELISA.
	Cynomolgus OSMR on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	Loaded Anti-OSMR Antibody, hFc Tag on ProA-Biosensor can bind Cynomolgus OSMR, His Tag with an affinity constant of 1.75 nM as determined in BLI assay (Gator® Prime).
	The purity of Cynomolgus OSMR is greater than 95% as determined by SEC-HPLC.