Name: Cynomolgus OSMR Protein (OSM-CM101)
Brand: KactusBio
SKU: OSM-CM101-100UG
Price: 315.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His
Purity: >95% as determined by Bis-Tris PAGE;>95% as determined by HPLC
Activity: Immobilized Cynomolgus OSMR, His Tag at 2 ug/ml (100 ul/well) on the plate. Dose response curve for Anti-OSMR Antibody, hFc Tag with the EC50 of 8.4 ng/ml determined by ELISA (QC Test). See testing image for detail.
Amino Acid Range: Glu28-Ser737

Catalog #OSM-CM101

Size

100UG

500UG

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Product Description	Recombinant Cynomolgus OSMR Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu28-Ser737.
Product Background	OSMR is targeted to the mitochondrial matrix via the presequence translocase-associated motor complex components, mtHSP70 and TIM44. OSMR interacts with NADH ubiquinone oxidoreductase 1/2 (NDUFS1/2) of complex I and promotes mitochondrial respiration. Deletion of OSMR impairs spare respiratory capacity, increases reactive oxygen species, and sensitizes BTSCs to IR-induced cell death.
Product Category	Recombinant Protein / Antibody discovery

Protein	OSMR
Synonyms	IL-31R subunit beta; IL-31R-beta; IL-31RB; OSMR beta; OSMR; OSMRB; OSMRBMGC150626; PLCA1 ;IL-31R subunit β; IL-31R-β; OSMR β
Accession	A0A2K5UFW5
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Glu28-Ser737
Molecular Weight	The protein has a predicted MW of 82.04 kDa. Due to glycosylation, the protein migrates to 110-130 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Cynomolgus OSMR, His Tag at 2 ug/ml (100 ul/well) on the plate. Dose response curve for Anti-OSMR Antibody, hFc Tag with the EC50 of 8.4 ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	>95% as determined by Bis-Tris PAGE;>95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Cynomolgus OSMR, His Tag at 2 ug/ml (100 ul/well) on the plate. Dose response curve for Anti-OSMR Antibody, hFc Tag with the EC50 of 8.4 ng/ml determined by ELISA (QC Test).
	Cynomolgus OSMR on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Cynomolgus OSMR is greater than 95% as determined by SEC-HPLC.