Cynomolgus OSMR Protein (OSM-CM101)
Cynomolgus OSMR Protein (OSM-CM101)
Cynomolgus OSMR Protein (OSM-CM101)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: >95% as determined by Bis-Tris PAGE;>95% as determined by HPLC
  • Activity: Immobilized Cynomolgus OSMR, His Tag at 2 ug/ml (100 ul/well) on the plate. Dose response curve for Anti-OSMR Antibody, hFc Tag with the EC50 of 8.4 ng/ml determined by ELISA (QC Test). See testing image for detail.
  • Amino Acid Range: Glu28-Ser737
Catalog #OSM-CM101
Regular price $315.00
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Product Description
Recombinant Cynomolgus OSMR Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu28-Ser737.
Product Background
OSMR is targeted to the mitochondrial matrix via the presequence translocase-associated motor complex components, mtHSP70 and TIM44. OSMR interacts with NADH ubiquinone oxidoreductase 1/2 (NDUFS1/2) of complex I and promotes mitochondrial respiration. Deletion of OSMR impairs spare respiratory capacity, increases reactive oxygen species, and sensitizes BTSCs to IR-induced cell death.
Product Category
Recombinant Protein
Target
OSMR
Accession
Species
Cynomolgus
Biotinylated
no
Amino Acid Range
Glu28-Ser737
Molecular Weight
The protein has a predicted MW of 82.04 kDa. Due to glycosylation, the protein migrates to 110-130 kDa based on Bis-Tris PAGE result.
Activity
Immobilized Cynomolgus OSMR, His Tag at 2 ug/ml (100 ul/well) on the plate. Dose response curve for Anti-OSMR Antibody, hFc Tag with the EC50 of 8.4 ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag
C-His
Express System
HEK293
Purity
>95% as determined by Bis-Tris PAGE;>95% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Cynomolgus OSMR, His Tag at 2 ug/ml (100 ul/well) on the plate. Dose response curve for Anti-OSMR Antibody, hFc Tag with the EC50 of 8.4 ng/ml determined by ELISA (QC Test).
Cynomolgus OSMR on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Cynomolgus OSMR is greater than 95% as determined by SEC-HPLC.

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