- Express System: Baculovirus-Insect Cells(Sf9)
- Product Tag: N-His
- Purity: > 90% as determined by Bis-Tris PAGE;> 85% as determined by HPLC
- Activity: Immobilized Cynomolgus PADI2, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-PADI2 Antibody, mFc Tag with the EC50 of 54.3ng/ml determined by ELISA.
- Amino Acid Range: Met1-Pro665
Cynomolgus PADI2 Protein (PAD-CB102) Summary
Product Description |
Recombinant Cynomolgus PADI2 Protein is expressed from Baculovirus-Insect Cells(Sf9) with His tag at the N-terminus.It contains Met1-Pro665. |
Product Background |
Peptidylarginine deiminases (PADs) are a group of enzymes that catalyze post-translational modifications of proteins by converting arginine residues into citrullines. PAD2 can be found in many tissues and organs, including brain, spinal cord, spleen , pancreas, skeletal muscles, secretory glands, and immune cells. By citrullinating proteins, PAD2 regulates a number of cellular processes such as gene transcription, antigen generation, extracellular trap formation (also termed ETosis), and pyroptosis. |
Cynomolgus PADI2 Protein (PAD-CB102) Specifications/Details
Protein |
PADI2 |
Synonyms |
Protein-arginine deiminase; KIAA0994; PAD-H19; PAD2; |
Accession |
|
Species |
Cynomolgus |
Biotinylated |
no |
Amino Acid Range |
Met1-Pro665 |
Molecular Weight |
The protein has a predicted MW of 77.08 kDa. The protein migrates to 70-85 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Cynomolgus PADI2, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-PADI2 Antibody, mFc Tag with the EC50 of 54.3ng/ml determined by ELISA. |
Product Tag |
N-His |
Fluorophore |
Unconjugated |
Expression System |
Baculovirus-Insect Cells(Sf9) |
Purity |
> 90% as determined by Bis-Tris PAGE;> 85% as determined by HPLC |
Endotoxin |
Less than 0.1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS, 10% glycerol (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
Other Available Proteins: