Cynomolgus PDGF R beta/CD140b Protein (PGF-CM1RB)
Cynomolgus PDGF R beta/CD140b Protein (PGF-CM1RB)
Cynomolgus PDGF R beta/CD140b Protein (PGF-CM1RB)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Cynomolgus PDGFR beta, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-PDGFRB Antibody, hFc Tag with the EC50 of 7.2ng/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Leu33-Lys531
Catalog #PGF-CM1RB
Regular price $300.00
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Product Description

Recombinant Cynomolgus PDGF R beta/CD140b Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu33-Lys531.

Product Background

Platelet-derived growth factor receptor (PDGFR) signaling is involved in proliferation and survival in a wide array of cell types.PDGFR-β signalling, via TGF-β signalling, may be crucial for restoration of BBB integrity after cerebral ischemia and therefore represents a novel potential therapeutic target.

Product Category

Recombinant Protein / Antibody discovery

Protein

PDGF R beta/CD140b

Synonyms

PDGF-R-beta; PDGFR-beta; PDGFRB; PDGF R beta; PDGFR-2; PDGFR-β

Accession

Species

Cynomolgus

Biotinylated

no

Amino Acid Range

Leu33-Lys531

Molecular Weight

The protein has a predicted MW of 57.49 kDa. Due to glycosylation, the protein migrates to 75-105 kDa based on Bis-Tris PAGE result.

Activity

Immobilized Cynomolgus PDGFR beta, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-PDGFRB Antibody, hFc Tag with the EC50 of 7.2ng/ml determined by ELISA. See testing image for detail.

Product Tag

C-His

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Cynomolgus PDGFR beta, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-PDGFRB Antibody, hFc Tag with the EC50 of 7.2ng/ml determined by ELISA. Immobilized Cynomolgus PDGFR beta, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-PDGFRB Antibody, hFc Tag with the EC50 of 7.2ng/ml determined by ELISA.
Cynomolgus PDGF R beta on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Cynomolgus PDGF R beta on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Cynomolgus PDGF R beta is greater than 95% as determined by SEC-HPLC. The purity of Cynomolgus PDGF R beta is greater than 95% as determined by SEC-HPLC.

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