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Cynomolgus PILRA Protein (PRA-CM101) Summary
Product Description |
Recombinant Cynomolgus PILRA Protein is expressed from HEK293 with His tag at the C-terminus.It contains Gln20-Ala188. |
Product Background |
Paired immunoglobulin-like type 2 receptor alpha (PILRΑ), which is mainly expressed on immune cells, including macrophages, dendritic cells and granulocytes, is related to regulation of broad immune responses. Bearing two immunoreceptor tyrosine-based inhibition motifs (ITIMs) in its cytoplasmic domain, PILRΑ functions to transmit inhibitory signals by recruiting SHP-1 and SHP-2, upon recognition of ligands such as CD99, neuronal differentiation proliferation factor-1 and CD8A, etc. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery/Others |
Cynomolgus PILRA Protein (PRA-CM101) Specifications/Details
Protein |
PILRA |
Synonyms |
PILRA; FDF03; PILRalpha; PILR-alpha |
Accession |
|
Species |
Cynomolgus |
Biotinylated |
no |
Amino Acid Range |
Gln20-Ala188 |
Molecular Weight |
The protein has a predicted MW of 20.17 kDa. Due to glycosylation, the protein migrates to 35-50 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Cynomolgus PILRA, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-PILRA Antibody, Rabbit IgG Tag with the EC50 of 75.5ng/ml determined by ELISA. |
Product Tag |
C-His |
Fluorophore |
Unconjugated |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 0.1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
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|
Immobilized Cynomolgus PILRA, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-PILRA Antibody, Rabbit IgG Tag with the EC50 of 75.5ng/ml determined by ELISA. |
|
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Cynomolgus PILRA on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
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The purity of Cynomolgus PILRA is greater than 95% as determined by SEC-HPLC. |
Other Available Proteins:
Finding available proteins...
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