• Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Cynomolgus PILRA, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-PILRA Antibody, Rabbit IgG Tag with the EC50 of 75.5ng/ml determined by ELISA.
  • Amino Acid Range: Gln20-Ala188
Catalog #PRA-CM101
Price
Regular price $37500
Regular price Sale price $37500
/
Size
Avantor VWR Fisher Scientific

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Cynomolgus PILRA Protein (PRA-CM101) Summary

Product Description

 Recombinant Cynomolgus PILRA Protein is expressed from HEK293 with His tag at the C-terminus.It contains Gln20-Ala188.

Product Background

 Paired immunoglobulin-like type 2 receptor alpha (PILRΑ), which is mainly expressed on immune cells, including macrophages, dendritic cells and granulocytes, is related to regulation of broad immune responses. Bearing two immunoreceptor tyrosine-based inhibition motifs (ITIMs) in its cytoplasmic domain, PILRΑ functions to transmit inhibitory signals by recruiting SHP-1 and SHP-2, upon recognition of ligands such as CD99, neuronal differentiation proliferation factor-1 and CD8A, etc.

Cynomolgus PILRA Protein (PRA-CM101) Specifications/Details

Protein
 PILRA
Synonyms
 PILRA; FDF03; PILRalpha; PILR-alpha
Accession
Species
 Cynomolgus
Biotinylated
 no
Amino Acid Range
 Gln20-Ala188
Molecular Weight
 The protein has a predicted MW of 20.17 kDa. Due to glycosylation, the protein migrates to 35-50 kDa based on Bis-Tris PAGE result.
Activity
 Immobilized Cynomolgus PILRA, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-PILRA Antibody, Rabbit IgG Tag with the EC50 of 75.5ng/ml determined by ELISA.
Product Tag
 C-His
Fluorophore
 Unconjugated
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 0.1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Liquid
Shipping
 Shipped with dry ice.
Formulation
 Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage
 Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Immobilized Cynomolgus PILRA, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-PILRA Antibody, Rabbit IgG Tag with the EC50 of 75.5ng/ml determined by ELISA. Immobilized Cynomolgus PILRA, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-PILRA Antibody, Rabbit IgG Tag with the EC50 of 75.5ng/ml determined by ELISA.
Cynomolgus PILRA on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Cynomolgus PILRA on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Cynomolgus PILRA is greater than 95% as determined by SEC-HPLC. The purity of Cynomolgus PILRA is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...