Cynomolgus PS20 Protein (PS2-CE120)

  • Express System: E.coli
  • Product Tag: N-His
  • Purity: > 95% as determined by Tris-Bis PAGE
  • Exact Sequence: Lys32-Gln192

Catalog: PS2-CE120

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Product Description Recombinant Cynomolgus PS20 Protein is expressed from E.coli with His tag at the N-Terminus.It contains Lys32-Gln192.

Product Background

The whey acidic protein family member, WFDC1/ps20 is a permissivity factor in HIV infection. Herein we describe a contrasting role for ps20 in limiting MHV-1 infection. Intranasal MHV-1 infection produces a respiratory infection in mice. Using ps20 knockout mice we provide evidence that intranasal MHV-1 infection results in increased lung viral titers in ps20(-/-) compared to ps20(/) mice. Roles for ps20 in regulating expression of neutrophil-specific chemotactic factors, thereby potentially modulating neutrophil migration, and in modulating neutrophil susceptibility to MHV-1 infection.

Product Category

Recombinant Protein

Target

PS20

Gene/Protein ID

XP_015298715.2

Species

Cynomolgus

Exact Sequence

Lys32-Gln192
Molecular Weight The protein has a predicted MW of 18.77 kDa. The protein migrates to 25-28 kDa based on Tris-Bis PAGE result.

Product Tag

N-His

Express System

E.coli
Purity > 95% as determined by Tris-Bis PAGE
Endotoxin Less than 1EU per ug by the LAL method.
Form Liquid
Shipping Shipped with dry ice.
Formulation Supplied as 0.22um filtered solution in 20mM PB, 500mM NaCl, 200mM Arginine (pH 7.4).
Stability And Storage Valid for 12 months from date of receipt when stored at -80°C.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Cynomolgus PS20 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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