Name: Cynomolgus PVRIG Protein (PVR-CM101)
Brand: KactusBio
SKU: PVR-CM101-100UG
Price: 330.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Cynomolgus PVRIG, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-PVRIG Antibody, hFc Tag with the EC50 of 2.0ng/ml determined by ELISA (QC Test). See testing image for detail.
Amino Acid Range: Thr41-Asp171

Catalog #PVR-CM101

Size

100UG

500UG

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Product Description	Recombinant Cynomolgus PVRIG Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Thr41-Asp171.
Product Background	PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family.PVRIG is a cell surface receptor for NECTIN2. May act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. Following interaction with NECTIN2, inhibits T-cell proliferation. Competes with CD226 for NECTIN2-binding.
Product Category	Recombinant Protein / Antibody discovery / Immune checkpoint proteins

Protein	PVRIG
Synonyms	C7orf15; CD112R; MGC104322; MGC138297; MGC2463; PVRIG; ALS2CR18; ALS2CR9; LPD; PREL-2; PREL2; RalGDS/AF-6; RMO1
Accession	A0A2K5WVV8
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Thr41-Asp171
Molecular Weight	The protein has a predicted MW of 14.78 kDa. Due to glycosylation, the protein migrates to 25-30 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Cynomolgus PVRIG, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-PVRIG Antibody, hFc Tag with the EC50 of 2.0ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Cynomolgus PVRIG, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-PVRIG Antibody, hFc Tag with the EC50 of 2.0ng/ml determined by ELISA (QC Test).
	Cynomolgus PVRIG on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Cynomolgus PVRIG is greater than 95% as determined by SEC-HPLC.