Cynomolgus PVRIG Protein (PVR-CM101)
Cynomolgus PVRIG Protein (PVR-CM101)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Cynomolgus PVRIG, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-PVRIG Antibody, hFc Tag with the EC50 of 2.0ng/ml determined by ELISA (QC Test). See testing image for detail.
  • Amino Acid Range: Thr41-Asp171
Catalog #PVR-CM101
Regular price $330.00
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Product Description
Recombinant Cynomolgus PVRIG Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Thr41-Asp171.
Product Background
PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family.PVRIG is a cell surface receptor for NECTIN2. May act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. Following interaction with NECTIN2, inhibits T-cell proliferation. Competes with CD226 for NECTIN2-binding.
Product Category
Recombinant Protein
Target
PVRIG
Accession
Species
Cynomolgus
Biotinylated
no
Amino Acid Range
Thr41-Asp171
Molecular Weight
The protein has a predicted MW of 14.78 kDa. Due to glycosylation, the protein migrates to 25-30 kDa based on Bis-Tris PAGE result.
Activity
Immobilized Cynomolgus PVRIG, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-PVRIG Antibody, hFc Tag with the EC50 of 2.0ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag
C-His
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Cynomolgus PVRIG, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-PVRIG Antibody, hFc Tag with the EC50 of 2.0ng/ml determined by ELISA (QC Test).
Cynomolgus PVRIG on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Cynomolgus PVRIG is greater than 95% as determined by SEC-HPLC.

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