Name: Cynomolgus/Rhesus macaque 4-1BB/TNFRSF9 Protein (BB4-CM141)
Brand: KactusBio
SKU: BB4-CM141-100UG
Price: 270.0 USD
Availability: InStock

Cynomolgus/Rhesus macaque 4-1BB/TNFRSF9 Protein (BB4-CM141)

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Cynomolgus/Rhesus macaque 4-1BB, His Tag at 0.2ug/ml (100ul/Well) on the plate. Dose response curve for Cynomolgus 4-1BB Ligand, hFc Tag with the EC50 of 3.3ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Leu24-Gln186

Catalog #BB4-CM141

Size

100UG

500UG

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Product Description	Recombinant Cynomolgus/Rhesus macaque 4-1BB/TNFRSF9 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu24-Gln186.
Product Background	4-1BB, is also known as CD137, is a type 2 transmembrane glycoprotein receptor belonging to the TNF superfamily.CD137 can be expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, CD137 expression is found on dendritic cells, B cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation.
Product Category	Recombinant Protein

Target	4-1BB/TNFRSF9
Synonyms	CD137; TNFRSF9; 4-1BB ligand receptor; 41BB; 4-1BB; CDw137; FLJ43501; ILA; T cell antigen ILA
Accession	XP_005544945.1
Species	Cynomolgus/Rhesus macaque
Biotinylated	no
Amino Acid Range	Leu24-Gln186
Molecular Weight	The protein has a predicted MW of 18.4 kDa. Due to glycosylation, the protein migrates to 30-40 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Cynomolgus/Rhesus macaque 4-1BB, His Tag at 0.2ug/ml (100ul/Well) on the plate. Dose response curve for Cynomolgus 4-1BB Ligand, hFc Tag with the EC50 of 3.3ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-His
Express System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Immobilized Cynomolgus/Rhesus macaque 4-1BB, His Tag at 0.2ug/ml (100ul/Well) on the plate. Dose response curve for Cynomolgus 4-1BB Ligand, hFc Tag with the EC50 of 3.3ng/ml determined by ELISA.
	Cynomolgus/Rhesus macaque 4-1BB on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Cynomolgus/Rhesus macaque 4-1BB is greater than 95% as determined by SEC-HPLC.

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