Cynomolgus/Rhesus macaque B7-H4 Protein (BH7-CM174)
Catalog: BH7-CM174
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| Product Description | Recombinant Cynomolgus/Rhesus macaque B7-H4 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe29-Ala258. |
Product Background |
B7-H4, also known as B7x and B7S1, is a 50-80 kDa glycosylated member of the B7 family of immunomodulatory proteins.B7-H4 is up-regulated in several carcinomas in correlation with tumor progression and metastasis. A soluble form of B7-H4 is elevated in the serum of ovarian cancer, renal cell carcinoma, and rheumatoid arthritis patients, also in correlation with advanced disease status-. |
Product Category |
Recombinant Protein |
Target |
B7-H4 |
Gene/Protein ID |
A0A2K5U6P5 / F7B770 |
Species |
Cynomolgus/Rhesus macaque |
Exact Sequence |
Phe29-Ala258 |
| Molecular Weight | The protein has a predicted MW of 26.41 kDa. Due to glycosylation, the protein migrates to 48-63 kDa based on Tris-Bis PAGE result. |
Activity |
Immobilized Cynomolgus/Rhesus macaque B7-H4, His Tag at 0.2ug/ml (100ul/Well) on the plate. Dose response curve for Anti-B7-H4 Antibody, hFc Tag with the EC50 of 12.8ng/ml determined by ELISA. See testing image for detail. |
Product Tag |
C-His |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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Immobilized Cynomolgus/Rhesus macaque B7-H4, His Tag at 0.2ug/ml (100ul/Well) on the plate. Dose response curve for Anti-B7-H4 Antibody, hFc Tag with the EC50 of 12.8ng/ml determined by ELISA. |
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The purity of Cynomolgus/Rhesus macaque B7-H4 is greater than 95% as determined by SEC-HPLC. |
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Cynomolgus/Rhesus macaque B7-H4 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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