• Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Activity: Immobilized Cynomolgus/Rhesus macaque CD19, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CD19 Antibody, hFc Tag with the EC50 of 1.16ug/ml determined by ELISA. The affinity constant of 0.26 uM as determined in SPR assay (Biacore T200).
  • Amino Acid Range: Gln21-Lys292
Catalog #CD1-CM129
Price
Regular price $413.00
Regular price Sale price $413.00
/
Size
Avantor VWR Fisher Scientific

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Cynomolgus/Rhesus macaque CD19 Protein (CD1-CM129) Summary

Product Description

 Recombinant Cynomolgus/Rhesus macaque CD19 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Gln21-Lys292.

Product Background

 CD19 is a 95 kDa transmembrane glycoprotein that plays a central role in B cell activation and humoral immune responses. Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens. Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca2+ stores.

Product Category

 Recombinant Protein / Antibody discovery / CAR-T targets, ADC targets

Cynomolgus/Rhesus macaque CD19 Protein (CD1-CM129) Specifications/Details

Protein
 CD19
Synonyms
 CD19; B4; CVID3; Leu-12; MGC12802
Accession
Species
 Cynomolgus/Rhesus macaque
Biotinylated
 no
Amino Acid Range
 Gln21-Lys292
Molecular Weight
 The protein has a predicted MW of 34.0 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Bis-Tris PAGE result.
Activity
 Immobilized Cynomolgus/Rhesus macaque CD19, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CD19 Antibody, hFc Tag with the EC50 of 1.16ug/ml determined by ELISA. The affinity constant of 0.26 uM as determined in SPR assay (Biacore T200).
Product Tag
 C-His

Fluorophore

 Unconjugated
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Liquid
Shipping
 Shipped with dry ice.
Formulation
 Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage
 Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Anti-CD19 Antibody, hFc Tag captured on CM5 Chip via Protein A can bind Cynomolgus/Rhesus macaque CD19, His Tag with an affinity constant of 0.26 uM as determined in SPR assay (Biacore T200). Anti-CD19 Antibody, hFc Tag captured on CM5 Chip via Protein A can bind Cynomolgus/Rhesus macaque CD19, His Tag with an affinity constant of 0.26 uM as determined in SPR assay (Biacore T200).
Immobilized Cynomolgus/Rhesus macaque CD19, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CD19 Antibody, hFc Tag with the EC50 of 1.16ug/ml determined by ELISA. Immobilized Cynomolgus/Rhesus macaque CD19, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CD19 Antibody, hFc Tag with the EC50 of 1.16ug/ml determined by ELISA.
Cynomolgus/Rhesus macaque CD19 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Cynomolgus/Rhesus macaque CD19 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
Loaded Anti-CD19 Antibody, hFc Tag on ProA-Biosensor can bind Cynomolgus/Rhesus macaque CD19, His Tag with an affinity constant of 0.43 µM as determined in BLI assay . Loaded Anti-CD19 Antibody, hFc Tag on ProA-Biosensor can bind Cynomolgus/Rhesus macaque CD19, His Tag with an affinity constant of 0.43 µM as determined in BLI assay .
Other Available Proteins:
Finding available proteins...
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