Regular price
$413.00
Order by 4pm ET for delivery on:
Cynomolgus/Rhesus macaque CD19 Protein (CD1-CM129) Summary
Product Description |
Recombinant Cynomolgus/Rhesus macaque CD19 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Gln21-Lys292. |
Product Background |
CD19 is a 95 kDa transmembrane glycoprotein that plays a central role in B cell activation and humoral immune responses. Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens. Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca2+ stores. |
Product Category |
Recombinant Protein / Antibody discovery / CAR-T targets, ADC targets |
Cynomolgus/Rhesus macaque CD19 Protein (CD1-CM129) Specifications/Details
Protein |
CD19 |
Synonyms |
CD19; B4; CVID3; Leu-12; MGC12802 |
Accession |
|
Species |
Cynomolgus/Rhesus macaque |
Biotinylated |
no |
Amino Acid Range |
Gln21-Lys292 |
Molecular Weight |
The protein has a predicted MW of 34.0 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Cynomolgus/Rhesus macaque CD19, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CD19 Antibody, hFc Tag with the EC50 of 1.16ug/ml determined by ELISA. The affinity constant of 0.26 uM as determined in SPR assay (Biacore T200). |
Product Tag |
C-His |
Fluorophore |
Unconjugated |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
|
|
Anti-CD19 Antibody, hFc Tag captured on CM5 Chip via Protein A can bind Cynomolgus/Rhesus macaque CD19, His Tag with an affinity constant of 0.26 uM as determined in SPR assay (Biacore T200). |
|
|
Immobilized Cynomolgus/Rhesus macaque CD19, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CD19 Antibody, hFc Tag with the EC50 of 1.16ug/ml determined by ELISA. |
|
|
Cynomolgus/Rhesus macaque CD19 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
Loaded Anti-CD19 Antibody, hFc Tag on ProA-Biosensor can bind Cynomolgus/Rhesus macaque CD19, His Tag with an affinity constant of 0.43 µM as determined in BLI assay . |
Other Available Proteins:
Finding available proteins...
Related Products
Have more questions?
Check out our Frequently Asked Questions page for more details about product specifications, ordering, and shipments.
Contact Us
Recommended Products
Loading...
Recently viewed
