Cynomolgus/Rhesus macaque CD27/TNFRSF7 Protein (CD2-CM227)
Catalog: CD2-CM227
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| Product Description | Recombinant Cynomolgus/Rhesus macaque CD27/TNFRSF7 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ala20-Arg191. |
Product Background |
CD27, also known as TNFRSF7, is an approximately 55 kDa transmembrane protein in the TNF receptor superfamily. It functions as a co‑stimulatory molecule that supports lymphocyte activation and survival. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. |
Product Category |
Recombinant Protein |
Target |
CD27/TNFRSF7 |
| Synonyms | CD27 antigen; Tp55; TNFRSF7; S152; T14; S152. LPFS2; MGC20393; S152CD27L receptor |
Gene/Protein ID |
XP_005569963.1 |
Species |
Cynomolgus/Rhesus macaque |
Exact Sequence |
Ala20-Arg191 |
| Molecular Weight | The protein has a predicted MW of 46.5 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result. |
Activity |
Immobilized Cynomolgus CD27 Ligand, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Cynomolgus/Rhesus macaque CD27, hFc Tag with the EC50 of 41.3ng/ml determined by ELISA. See testing image for detail. |
Product Tag |
C-hFc |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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Immobilized Cynomolgus CD27 Ligand, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Cynomolgus/Rhesus macaque CD27, hFc Tag with the EC50 of 41.3ng/ml determined by ELISA. |
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The purity of Cynomolgus/Rhesus macaque CD27 is greater than 95% as determined by SEC-HPLC. |
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Cynomolgus/Rhesus macaque CD27 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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