Name: Cynomolgus/Rhesus macaque DKK1 Protein (DKK-CM101)
Brand: KactusBio
SKU: DKK-CM101-100UG
Price: 270.0 USD
Availability: InStock

Cynomolgus/Rhesus macaque DKK1 Protein (DKK-CM101)

Immobilized Cynomolgus/Rhesus macaque DKK1, His Tag at 0.2ug/ml (100ul/Well) on the plate. Dose response curve for Anti-DKK1 Antibody, hFc Tag with the EC50 of 5.6ng/ml determined by ELISA (QC Test).

Cynomolgus/Rhesus macaque DKK1 Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE
Activity: Immobilized Cynomolgus/Rhesus macaque DKK1, His Tag at 0.2ug/ml (100ul/Well) on the plate. Dose response curve for Anti-DKK1 Antibody, hFc Tag with the EC50 of 5.6ng/ml determined by ELISA (QC Test). See testing image for detail.
Amino Acid Range: Thr32-His266

Catalog #DKK-CM101

Size

100UG

500UG

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Product Description	Recombinant Cynomolgus/Rhesus macaque DKK1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Thr32-His266.
Product Background	Dickkopf related protein 1 (Dkk-1) is the founding member of the Dickkopf family of proteins that includes Dkk-1, -2, -3, -4, and a related protein, Soggy. Dkk proteins are secreted proteins that contain two conserved cysteine-rich domains separated by a linker region. Dkk antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation.
Product Category	Recombinant Protein / Antibody discovery

Protein	DKK1
Synonyms	Dickkopf-1; Dkk1; SK
Accession	XP_005565907.1(Cynomolgus) / NP_001247454.1(Rhesus macaque)
Species	Cynomolgus/Rhesus macaque
Biotinylated	no
Amino Acid Range	Thr32-His266
Molecular Weight	The protein has a predicted MW of 26.85 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Cynomolgus/Rhesus macaque DKK1, His Tag at 0.2ug/ml (100ul/Well) on the plate. Dose response curve for Anti-DKK1 Antibody, hFc Tag with the EC50 of 5.6ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Cynomolgus/Rhesus macaque DKK1, His Tag at 0.2ug/ml (100ul/Well) on the plate. Dose response curve for Anti-DKK1 Antibody, hFc Tag with the EC50 of 5.6ng/ml determined by ELISA (QC Test).
	Cynomolgus/Rhesus macaque DKK1 Bis-Tris PAGE under reduced condition. The purity is greater than 95%.