Cynomolgus/Rhesus macaque Her3 Protein (HER-CM403)
Cynomolgus/Rhesus macaque Her3 Protein (HER-CM403)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Cynomolgus/Rhesus macaque Her3, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-Her3 Antibody, hFc Tag with the EC50 of 20.1ng/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Ser20-His641
Catalog #HER-CM403
Regular price $270.00
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Product Description
Recombinant Cynomolgus/Rhesus macaque Her3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser20-His641.
Product Background
Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG).
Product Category
Recombinant Protein
Target
Her3
Synonyms
ErbB3; ErbB-3; HER3; HER3c-erbB-3; LCCS2; MDA-BF-1; MGC88033; p180-ErbB3; p45-sErbB3; p85-sErbB3; ERBB3
Accession
Species
Cynomolgus/Rhesus macaque
Biotinylated
no
Amino Acid Range
Ser20-His641
Molecular Weight
The protein has a predicted MW of 69.54 kDa. Due to glycosylation, the protein migrates to 85-105 kDa based on Bis-Tris PAGE result.
Activity
Immobilized Cynomolgus/Rhesus macaque Her3, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-Her3 Antibody, hFc Tag with the EC50 of 20.1ng/ml determined by ELISA. See testing image for detail.
Product Tag
C-His
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Cynomolgus/Rhesus macaque Her3, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-Her3 Antibody, hFc Tag with the EC50 of 20.1ng/ml determined by ELISA.
Immobilized Cynomolgus/Rhesus macaque Her3, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human NRG1 Beta 1, hFc Tag with the EC50 of 0.12ug/ml determined by ELISA (QC Test).
Cynomolgus/Rhesus macaque Her3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Cynomolgus/Rhesus macaque Her3 is greater than 95% as determined by SEC-HPLC.

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