Name: Cynomolgus/Rhesus macaque TNFSF15 Protein (FSF-CM115)
Brand: KactusBio
SKU: FSF-CM115-100UG
Price: 315.0 USD
Availability: InStock

Cynomolgus/Rhesus macaque TNFSF15 Protein (FSF-CM115)

Mouse DR3, His Tag immobilized on CM5 Chip can bind Cynomolgus/Rhesus macaque TNFSF15, His Tag with an affinity constant of 11.70 nM as determined in SPR assay (Biacore T200).

Immobilized Cynomolgus/Rhesus macaque TNFSF15, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-TNFSF15 Antibody, hFc Tag with the EC50 of 3.0ng/ml determined by ELISA (QC Test).

Cynomolgus/Rhesus macaque TNFSF15 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Cynomolgus/Rhesus macaque TNFSF15 is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: N-His
Purity: >95% as determined by Bis-Tris PAGE;>95% as determined by HPLC
Activity: Immobilized Cynomolgus/Rhesus macaque TNFSF15, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-TNFSF15 Antibody, hFc Tag with the EC50 of 3.0ng/ml determined by ELISA (QC Test). The affinity constant of 11.70 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Leu72-Leu251

Catalog #FSF-CM115

Size

100UG

500UG

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Product Description	Recombinant Cynomolgus/Rhesus macaque TNFSF15 Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Leu72-Leu251.
Product Background	TNF superfamily member 15 (TNFSF15), a cytokine largely produced by vascular endothelial cells and a specific inhibitor of the proliferation of these same cells, can inhibit VEGF-induced vascular permeability in vitro and in vivo, and that death receptor 3 (DR3), a cell surface receptor of TNFSF15, mediates TNFSF15-induced dephosphorylation of VEGFR2.
Product Category	Recombinant Protein / Antibody discovery

Protein	TNFSF15
Synonyms	TL1A; VEGI-251; TNFSF15; TL1; VEGI; VEGI192A; TNF superfamily member 15
Accession	A0A2K5UA22(Cynomolgus) / F6S8F9(Rhesus macaque)
Species	Cynomolgus/Rhesus macaque
Biotinylated	no
Amino Acid Range	Leu72-Leu251
Molecular Weight	The protein has a predicted MW of 21.52 kDa. Due to glycosylation, the protein migrates to 25-35 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Cynomolgus/Rhesus macaque TNFSF15, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-TNFSF15 Antibody, hFc Tag with the EC50 of 3.0ng/ml determined by ELISA (QC Test). The affinity constant of 11.70 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	N-His
Expression System	HEK293
Purity	>95% as determined by Bis-Tris PAGE;>95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Mouse DR3, His Tag immobilized on CM5 Chip can bind Cynomolgus/Rhesus macaque TNFSF15, His Tag with an affinity constant of 11.70 nM as determined in SPR assay (Biacore T200).
	Immobilized Cynomolgus/Rhesus macaque TNFSF15, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-TNFSF15 Antibody, hFc Tag with the EC50 of 3.0ng/ml determined by ELISA (QC Test).
	Cynomolgus/Rhesus macaque TNFSF15 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Cynomolgus/Rhesus macaque TNFSF15 is greater than 95% as determined by SEC-HPLC.