ELISA binding curve of Cynomolgus SEZ6 (His tag) with anti-SEZ6 antibody, showing absorbance at OD450 vs. antibody concentration.
Cynomolgus SEZ6 Protein (SEZ-CM106)
Cynomolgus SEZ6 Protein (SEZ-CM106)
Cynomolgus SEZ6 Protein (SEZ-CM106)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Cynomolgus SEZ6, His Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Anti-SEZ6 Antibody, hFc Tag with the EC50 of 4.5ng/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Leu20-His927
Catalog #SEZ-CM106
Regular price $346.50
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Product Description

Recombinant Cynomolgus SEZ6 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu20-His927.

Product Background

Seizure-related protein 6 (Sez6) contributes to chronic pain development as sez6 knockout mice show attenuated pain behaviours after peripheral nerve injury, compared with control mice. The type I transmembrane isoform of Sez6 is cleaved by the β-amyloid precursor protein cleavage enzyme 1 (BACE1), resulting in Sez6 extracellular domain shedding from the neuron surface.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others
Protein
SEZ6
Synonyms
SEZ-6; SEZ6; BSRPC; BSRP-C;
Accession
Species
Cynomolgus
Biotinylated
no
Amino Acid Range
Leu20-His927
Molecular Weight
The protein has a predicted MW of 99.11 kDa. Due to glycosylation, the protein migrates to 150-180 kDa based on Bis-Tris PAGE result.
Activity
Immobilized Cynomolgus SEZ6, His Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Anti-SEZ6 Antibody, hFc Tag with the EC50 of 4.5ng/ml determined by ELISA. See testing image for detail.

Product Tag

C-His
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Cynomolgus SEZ6, His Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Anti-SEZ6 Antibody, hFc Tag with the EC50 of 4.5ng/ml determined by ELISA. Immobilized Cynomolgus SEZ6, His Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Anti-SEZ6 Antibody, hFc Tag with the EC50 of 4.5ng/ml determined by ELISA.
Cynomolgus SEZ6 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Cynomolgus SEZ6 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
Loaded Anti-SEZ6 Antibody, hFc Tag on ProA-Biosensor can bind Cynomolgus SEZ6, His Tag with an affinity constant of 17.50 nM as determined in BLI assay (Gator® Prime). Loaded Anti-SEZ6 Antibody, hFc Tag on ProA-Biosensor can bind Cynomolgus SEZ6, His Tag with an affinity constant of 17.50 nM as determined in BLI assay (Gator® Prime).
The purity of Cynomolgus SEZ6 is greater than 95% as determined by SEC-HPLC. The purity of Cynomolgus SEZ6 is greater than 95% as determined by SEC-HPLC.
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