Name: Cynomolgus Siglec-15/CD33L3 Protein (SIG-CM415)
Brand: KactusBio
SKU: SIG-CM415-100UG
Price: 315.0 USD
Availability: InStock

Cynomolgus Siglec-15/CD33L3 Protein (SIG-CM415)

Express System: HEK293
Product Tag: C-His-Avi
Purity: > 95% as determined by Bis-Tris PAGE
Activity: Immobilized Cynomolgus Siglec-15, His Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Anti-Siglec-15 Antibody, hFc Tag with the EC50 of 3.8ng/ml determined by ELISA (QC Test). See testing image for detail.
Amino Acid Range: Met60-Thr322

Catalog #SIG-CM415

Size

100UG

500UG

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Product Description	Recombinant Cynomolgus Siglec-15/CD33L3 Protein is expressed from HEK293 with His and Avi tag at the C-Terminus.It contains Met60-Thr322.
Product Background	Siglec-15 is a transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory molecules. Mature human Siglec-15 consists of a 244 amino acid extracellular domain (ECD) with two Ig-like domains, a 21 aa transmembrane segment, and a 44 aa cytoplasmic domain. Siglec-15 is a potential therapeutic target for osteoporosis and plays a conserved regulatory role in the immune system of vertebrates.
Product Category	Recombinant Protein

Target	Siglec-15/CD33L3
Synonyms	CD33 molecule-like 3; CD33L3; HsT1361; Siglec15; CD33 antigen-like 3; SIGLEC-15
Accession	XP_005586866.2
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Met60-Thr322
Molecular Weight	The protein has a predicted MW of 29.2 kDa. Due to glycosylation, the protein migratesto 33-43 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Cynomolgus Siglec-15, His Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Anti-Siglec-15 Antibody, hFc Tag with the EC50 of 3.8ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag	C-His-Avi
Express System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22um filtered solution in 20mM PB, 500mM NaCl, 0.1M L-arginine (pH 6.0).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Cynomolgus Siglec-15, His Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Anti-Siglec-15 Antibody, hFc Tag with the EC50 of 3.8ng/ml determined by ELISA (QC Test).
	Cynomolgus Siglec-15 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

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