Name: Cynomolgus SOST/Sclerostin Protein (SOT-CM101)
Brand: KactusBio
SKU: SOT-CM101-100UG
Price: 330.0 USD
Availability: InStock

Cynomolgus SOST/Sclerostin Protein (SOT-CM101)

Immobilized Cynomolgus SOST, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human LRP-6, mFc Tag with the EC50 of 16.9ng/ml determined by ELISA (QC Test).

Immobilized Cynomolgus SOST, His Tag at 0.2ug/ml (100ul/Well) on the plate. Dose response curve for Anti-SOST Antibody, hFc Tag with the EC50 of 10.0ng/ml determined by ELISA.

Cynomolgus SOST on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE
Activity: Immobilized Cynomolgus SOST, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human LRP-6, mFc Tag with the EC50 of 16.9ng/ml determined by ELISA (QC Test). See testing image for detail.
Amino Acid Range: Gln69-Tyr258

Catalog #SOT-CM101

Size

100UG

500UG

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Product Description	Recombinant Cynomolgus SOST/Sclerostin Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln69-Tyr258.
Product Background	SOST, also known as sclerostin, is a member of the cerberus/DAN family, a group of secreted glycoproteins characterized by a cysteine-knot motif. SOST is negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Protein	SOST/Sclerostin
Synonyms	sclerostin; SOST; VBCHsclerosteosis; CDD; DAND6; SOST1; VBCH
Accession	XP_005584428.2
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Gln69-Tyr258
Molecular Weight	The protein has a predicted MW of 22.58 kDa. Due to glycosylation, the protein migrates to 30-40 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Cynomolgus SOST, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human LRP-6, mFc Tag with the EC50 of 16.9ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Cynomolgus SOST, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human LRP-6, mFc Tag with the EC50 of 16.9ng/ml determined by ELISA (QC Test).
	Immobilized Cynomolgus SOST, His Tag at 0.2ug/ml (100ul/Well) on the plate. Dose response curve for Anti-SOST Antibody, hFc Tag with the EC50 of 10.0ng/ml determined by ELISA.
	Cynomolgus SOST on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.