Name: Cynomolgus SOST/Sclerostin Protein, Ultra Low Endotoxin (SOT-CM101-UL)
Brand: KactusBio
SKU: SOT-CM101-UL-100UG
Price: 363.0 USD
Availability: InStock

Cynomolgus SOST/Sclerostin Protein, Ultra Low Endotoxin (SOT-CM101-UL)

Immobilized Cynomolgus SOST, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human LRP-6, mFc Tag with the EC50 of 16.9ng/ml determined by ELISA (QC Test).

Immobilized Cynomolgus SOST, His Tag at 0.2ug/ml (100ul/Well) on the plate. Dose response curve for Anti-SOST Antibody, hFc Tag with the EC50 of 10.0ng/ml determined by ELISA.

Cynomolgus SOST on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE
Activity: Immobilized Cynomolgus SOST, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human LRP-6, mFc Tag with the EC50 of 16.9ng/ml determined by ELISA (QC Test). See testing image for detail.
Amino Acid Range: Gln69-Tyr258

Catalog #SOT-CM101-UL

Size

100UG

500UG

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Product Description	Recombinant Cynomolgus SOST/Sclerostin Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln69-Tyr258.
Product Background	SOST, also known as sclerostin, is a member of the cerberus/DAN family, a group of secreted glycoproteins characterized by a cysteine-knot motif. SOST is negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Protein	SOST/Sclerostin
Synonyms	sclerostin; SOST; VBCHsclerosteosis; CDD; DAND6; SOST1; VBCH
Accession	XP_005584428.2
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Gln69-Tyr258
Molecular Weight	The protein has a predicted MW of 22.58 kDa. Due to glycosylation, the protein migrates to 30-40 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Cynomolgus SOST, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human LRP-6, mFc Tag with the EC50 of 16.9ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 0.01 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Cynomolgus SOST, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human LRP-6, mFc Tag with the EC50 of 16.9ng/ml determined by ELISA (QC Test).
	Immobilized Cynomolgus SOST, His Tag at 0.2ug/ml (100ul/Well) on the plate. Dose response curve for Anti-SOST Antibody, hFc Tag with the EC50 of 10.0ng/ml determined by ELISA.
	Cynomolgus SOST on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.