Name: Cynomolgus TLR3 Protein (TLR-CM103)
Brand: KactusBio
SKU: TLR-CM103-100UG
Price: 315.0 USD
Availability: InStock

Catalog #TLR-CM103

Size

100UG

500UG

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Product Description	Recombinant Cynomolgus TLR3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser31-Glu711.
Product Background	TLR3 is expressed in the central nervous system (CNS), where it is required to control HSV-1, which spreads from the epithelium to the CNS via cranial nerves. TLR3 is also expressed in epithelial and dendritic cells, which apparently use TLR3-independent pathways to prevent further dissemination of HSV-1 and to provide resistance to other pathogens in TLR3-deficient patients. Human TLR3 appears to be redundant in host defense to most microbes but is vital for natural immunity to HSV-1 in the CNS, which suggests that neurotropic viruses have contributed to the evolutionary maintenance of TLR3.
Product Category	Recombinant Protein / Antibody discovery

Protein	TLR3
Synonyms	TLR3; CD283; IIAE2
Accession	A0A2K5WT39
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Ser31-Glu711
Molecular Weight	The protein has a predicted MW of 78.04 kDa. Due to glycosylation, the protein migrates to 95-115 kDa based on Bis-Tris PAGE result.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Cynomolgus TLR3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Cynomolgus TLR3 is greater than 95% as determined by SEC-HPLC.