Cynomolgus TREM1 Protein (TRM-CM101)

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Activity: Immobilized Cynomolgus TREM1, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human PGLYRP1, hFc Tag with the EC50 of 1.14ug/ml determined by ELISA. See testing image for detail.
Exact Sequence: Thr21-Pro201

Catalog: TRM-CM101

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Product Description	Recombinant Cynomolgus TREM1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Thr21-Pro201.
Product Background	TREM1 (Triggering Receptor Expressed on Myeloid Cells 1) is a pro-inflammatory receptor expressed by phagocytes, which can also be released as a soluble molecule (sTREM1). The roles of TREM1 and sTREM1 in liver infection and inflammation are not clear.
Product Category	Recombinant Protein

Target	TREM1
Synonyms	CD354; TREM-1
Gene/Protein ID	XP_005553111.1
Species	Cynomolgus
Exact Sequence	Thr21-Pro201
Molecular Weight	The protein has a predicted MW of 23.76 kDa. Due to glycosylation, the protein migrates to 45-60 kDa based on Tris-Bis PAGE result.
Activity	Immobilized Cynomolgus TREM1, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human PGLYRP1, hFc Tag with the EC50 of 1.14ug/ml determined by ELISA. See testing image for detail.
Product Tag	C-His
Express System	HEK293
Purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Immobilized Cynomolgus TREM1, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human PGLYRP1, hFc Tag with the EC50 of 1.14ug/ml determined by ELISA.
	The purity of Cynomolgus TREM1 is greater than 95% as determined by SEC-HPLC.
	Cynomolgus TREM1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.