Regular price
$346.50
Order by 4pm ET for delivery on:
Cynomolgus TSLP Protein, Ultra Low Endotoxin (TSP-CM101-UL) Summary
Product Description |
Recombinant Cynomolgus TSLP Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Tyr29-Gln159. |
Product Background |
Thymic Stromal Lymphopoietin (TSLP) was originally identified as an activity from the conditioned medium of a mouse thymic stromal cell line that promoted the development of B cells. Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c dendritic cells. Can induce allergic inflammation by directly activating mast cells. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery/Others |
Cynomolgus TSLP Protein, Ultra Low Endotoxin (TSP-CM101-UL) Specifications/Details
Protein |
TSLP |
Synonyms |
thymic stromal lymphopoietin; TSLP |
Accession |
|
Species |
Cynomolgus |
Biotinylated |
no |
Amino Acid Range |
Tyr29-Gln159 |
Molecular Weight |
The protein has a predicted MW of 16.3 kDa. Due to furin cleavage site, the protein migrates to 12 kDa&23-30 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Cynomolgus TSLP, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human TSLPR, hFc Tag with the EC50 of 0.52ng/ml determined by ELISA. |
Product Tag |
C-His |
Fluorophore |
Unconjugated |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC |
Endotoxin |
Less than 0.01 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
|
|
Immobilized Cynomolgus TSLP, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human TSLPR, hFc Tag with the EC50 of 0.52ng/ml determined by ELISA. |
|
|
Immobilized Cynomolgus TSLP, His Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Anti-TSLP Antibody, hFc Tag with the EC50 of 13.6ng/ml determined by ELISA. |
|
|
Cynomolgus TSLP on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
Loaded Human TSLPR, hFc Tag on ProA-Biosensor can bind Cynomolgus TSLP, His Tag with an affinity constant of 6.58 nM as determined in BLI assay. |
|
|
Loaded Anti-TSLP Antibody, hFc Tag on ProA-Biosensor can bind Cynomolgus TSLP, His Tag with an affinity constant of 2.02 nM as determined in BLI assay. |
|
|
The purity of Cynomolgus TSLP is greater than 90% as determined by SEC-HPLC. |
Other Available Proteins:
Finding available proteins...
Related Products
Have more questions?
Check out our Frequently Asked Questions page for more details about product specifications, ordering, and shipments.
Contact Us
Recommended Products
Loading...
Recently viewed
