- Express System: HEK293
- Product Tag: C-His
- Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
- Activity: Immobilized Human TSLPR, hFc Tag at 2ug/ml(100ul/well) on the plate. Dose response curve for Cynomolgus TSLP, His Tag with the EC50 of 2.2ng/ml determined by ELISA. See testing image for detail.
- Amino Acid Range: Tyr29-Gln159(R127A, R130S)
Product Description |
Recombinant Cynomolgus TSLP (R127A, R130S) Protein is expressed from HEK293 with His tag at the C-terminus.It contains Tyr29-Gln159 (R127A, R130S). |
Product Background |
Thymic Stromal Lymphopoietin (TSLP) was originally identified as an activity from the conditioned medium of a mouse thymic stromal cell line that promoted the development of B cells. Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c dendritic cells. Can induce allergic inflammation by directly activating mast cells. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery | Others |
Protein |
TSLP |
Synonyms |
thymic stromal lymphopoietin; TSLP |
Accession |
|
Species |
Cynomolgus |
Biotinylated |
no |
Amino Acid Range |
Tyr29-Gln159(R127A, R130S) |
Molecular Weight |
The protein has a predicted MW of 16.65 kDa. Due to glycosylation, the protein migrates to 25-40 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Human TSLPR, hFc Tag at 2ug/ml(100ul/well) on the plate. Dose response curve for Cynomolgus TSLP, His Tag with the EC50 of 2.2ng/ml determined by ELISA. See testing image for detail. |
Product Tag |
C-His |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 0.1 EU per ug by the LAL method. |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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