Product Description |
Recombinant Human CCR4 Protein-Nanodisc is expressed from HEK293 with His tag at the C-terminus (FITC-equivalent protein is fused on cytoplasmic part).It contains Met1-Leu360. |
Product Background |
CC chemokine receptor 4 (CCR4) is a chemokine receptor mainly expressed by T cells. CCR4 is important in the pathogenesis of many diseases, such as diabetes, multiple sclerosis, asthma, dermatitis, and cancer. This review briefly characterizes CCR4 and its ligands (CCL17, CCL22, and CCL2), and their contributions to immunological and neoplastic diseases. |
Product Category |
Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / Nanodisc |
Protein |
CCR4 |
Synonyms |
C-C CKR-4; CC-CKR-4; CCR-4; CCR4; K5-5; CD194; CMKBR4; CKR-4 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Met1-Leu360 |
Molecular Weight |
The protein has a predicted MW of 69.20 kDa. |
Activity |
Immobilized Human CCR4 Nanodisc, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-CCR4 Antibody, hFc Tag with the EC50 of 10.6ng/ml determined by ELISA (QC Test). See testing image for detail. |
Product Tag |
C-His |
Expression System |
HEK293 |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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Immobilized Human CCR4 Nanodisc, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-CCR4 Antibody, hFc Tag with the EC50 of 10.6ng/ml determined by ELISA (QC Test). |
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