Name: Human CCR4 Protein-Nanodisc (CR4-HM1N122)
Brand: KactusBio
SKU: CR4-HM1N122-100UG
Price: 1444.3 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His
Activity: Immobilized Human CCR4 Nanodisc, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-CCR4 Antibody, hFc Tag with the EC50 of 11.3ng/ml determined by ELISA. The affinity constant of 0.22 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Met1-Leu360

Catalog #CR4-HM1N122

Size

100UG

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Product Description	Recombinant Human CCR4 Protein-Nanodisc is expressed from HEK293 with His tag at the C-terminus (FITC-equivalent protein is fused on cytoplasmic part).It contains Met1-Leu360.
Product Background	CC chemokine receptor 4 (CCR4) is a chemokine receptor mainly expressed by T cells. CCR4 is important in the pathogenesis of many diseases, such as diabetes, multiple sclerosis, asthma, dermatitis, and cancer. This review briefly characterizes CCR4 and its ligands (CCL17, CCL22, and CCL2), and their contributions to immunological and neoplastic diseases.
Product Category	Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / Nanodisc

Protein	CCR4
Synonyms	C-C CKR-4; CC-CKR-4; CCR-4; CCR4; K5-5; CD194; CMKBR4; CKR-4
Accession	P51679
Species	Human
Biotinylated	no
Amino Acid Range	Met1-Leu360
Molecular Weight	The protein has a predicted MW of 69.20 kDa.
Activity	Immobilized Human CCR4 Nanodisc, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-CCR4 Antibody, hFc Tag with the EC50 of 11.3ng/ml determined by ELISA. The affinity constant of 0.22 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in PBS (pH 7.4) / PBS, 200mM L-Arginine (pH 7.4). Notice: Not recommended for flow cytometry in mammalian cells.
Stability And Storage	Valid for 6 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human CCR4 Nanodisc, His Tag captured on CM5 Chip via Anti-His Antibody can bind Anti-CCR4 Antibody, hFc Tag with an affinity constant of 0.22 nM as determined in SPR assay (Biacore T200).
	Immobilized Human CCR4 Nanodisc, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-CCR4 Antibody, hFc Tag with the EC50 of 11.3ng/ml determined by ELISA.