FITC-equivalent Human CXCR5 Protein-Nanodisc (CXR5-HM1N72)
  • Express System: HEK293
  • Product Tag: C-His
  • Activity: Immobilized FITC-equivalent Human CXCR5, His Tag at 5ug/ml(100ul/well) on the plate. Dose response curve for Anti-CXCR5 Antibody, hFc Tag with the EC50 of 11.7ng/ml determined by ELISA (QC Test). See testing image for detail.
  • Amino Acid Range: Met1-Phe372
Catalog #CXR5-HM1N72
Regular price $1,313.00
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Product Description

Recombinant FITC-equivalent Human CXCR5 Protein-Nanodisc is expressed from HEK293 with His tag at the C-terminus.It contains Met1-Phe372.

Product Background

CXCR5 is a serpentine receptor implicated in cell migration in lymphocytes and differentiation in leukocytes. It causes MAPK pathway activation and has known membrane partners for signaling. CXCR5 is also expressed in HL-60 cells, a human acute myeloid leukemia line, following treatment with all-trans retinoic acid, which induces differentiation toward a neutrophil-like state. CXCR5 is necessary for this process; differentiation was crippled in CXCR5 knockout cells and enhanced in cells ectopically expressing it.

Product Category

Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / Nanodisc

Protein

CXCR5

Synonyms

CXC-R5; CXCR-5; MDR-15; MDR15; CD185; BLR1

Accession

Species

Human

Biotinylated

no

Amino Acid Range

Met1-Phe372

Molecular Weight

The protein has a predicted MW of 43.3 kDa.

Activity

Immobilized FITC-equivalent Human CXCR5, His Tag at 5ug/ml(100ul/well) on the plate. Dose response curve for Anti-CXCR5 Antibody, hFc Tag with the EC50 of 11.7ng/ml determined by ELISA (QC Test). See testing image for detail.

Product Tag

C-His

Fluorophore

FITC

Expression System

HEK293

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in PBS (pH 7.4). Notice: Not recommended for immunization.
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized FITC-equivalent Human CXCR5, His Tag at 5ug/ml(100ul/well) on the plate. Dose response curve for Anti-CXCR5 Antibody, hFc Tag with the EC50 of 11.7ng/ml determined by ELISA (QC Test). Immobilized FITC-equivalent Human CXCR5, His Tag at 5ug/ml(100ul/well) on the plate. Dose response curve for Anti-CXCR5 Antibody, hFc Tag with the EC50 of 11.7ng/ml determined by ELISA (QC Test).

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