FITC-equivalent Human GLP-1R Protein-Nanodisc (GLP-HM1N123)
  • Express System: HEK293
  • Product Tag: C-His
  • Activity: Immobilized Anti-GLP-1R Antibody, hFc Tag at 5ug/ml(100ul/well) on the plate. Dose response curve for FITC-equivalent Human GLP-1R Nanodisc, His Tag with the EC50 of 0.36ug/ml determined by ELISA (QC Test). See testing image for detail.
  • Amino Acid Range: Met1-Ser463
Catalog #GLP-HM1N123
Regular price $1,875.00
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Product Description

Recombinant FITC-equivalent Human GLP-1R Protein-Nanodisc is expressed from HEK293 with His tag at the C-terminus.It contains Met1-Ser463.

Product Background

Glucagon-like peptide-1 receptor (GLP-1R) is a critical therapeutic target for type 2 diabetes mellitus (T2DM). GLP-1R emerged as an important pharmacological target for addressing T2DM, as it actively contributes to maintaining glucose homeostasis while promoting both β cell proliferation and insulin release. The impact of GLP-1R agonists such as semaglutide extends beyond diabetes control: they play a multifaceted role in regulating blood glucose levels by reducing hunger, moderating food intake, and managing body weight. Notably, GLP-1R agonists inhibit cancer progression in some malignant tumors.

Product Category

Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / Nanodisc

Protein

GLP-1R

Synonyms

GLP-1 receptor; GLP-1-R; GLP-1R; GLP1R

Accession

Species

Human

Biotinylated

no

Amino Acid Range

Met1-Ser463

Molecular Weight

The protein has a predicted MW of 80.9 kDa.

Activity

Immobilized Anti-GLP-1R Antibody, hFc Tag at 5ug/ml(100ul/well) on the plate. Dose response curve for FITC-equivalent Human GLP-1R Nanodisc, His Tag with the EC50 of 0.36ug/ml determined by ELISA (QC Test). See testing image for detail.

Product Tag

C-His

Fluorophore

FITC

Expression System

HEK293

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in PBS (pH 7.4). Notice: Not recommended for immunization.
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Anti-GLP-1R Antibody, hFc Tag at 5ug/ml(100ul/well) on the plate. Dose response curve for FITC-equivalent Human GLP-1R Nanodisc, His Tag with the EC50 of 0.36ug/ml determined by ELISA (QC Test). Immobilized Anti-GLP-1R Antibody, hFc Tag at 5ug/ml(100ul/well) on the plate. Dose response curve for FITC-equivalent Human GLP-1R Nanodisc, His Tag with the EC50 of 0.36ug/ml determined by ELISA (QC Test).

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