FITC-Labeled Human HLA-A*11:01&B2M&KRAS G12V (VVGAVGVGK) Tetramer Prot

Express System: E.coli
Product Tag: C-His-Avi
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Amino Acid Range: Gly25-Thr305(HLA-A*11:01), Ile21-Met119(B2M) and VVGAVGVGK peptide

Catalog #MHC-HE006TF

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$1,050.00

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FITC-Labeled Human HLA-A*11:01&B2M&KRAS G12V (VVGAVGVGK) Tetramer Protein (MHC-HE006TF) Summary

Product Description	Recombinant FITC-Labeled Human HLA-A11:01&B2M&KRAS G12V (VVGAVGVGK) Tetramer Protein is expressed from E.coli with His tag and Avi tag at the C-terminus. FITC-Labeled Human HLA-A11:01&B2M&KRAS G12V (VVGAVGVGK) Tetramer is assembled by biotinylated monomer and FITC-labeled streptavidin.It contains Gly25-Thr305(HLA-A*11:01), Ile21-Met119(B2M) and VVGAVGVGK peptide.
Product Background	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
Product Category	Recombinant Protein / Antibody discovery / MHC / Peptide-MHCs

Protein	HLA-A*11:01&B2M&KRAS G12V (VVGAVGVGK)
Synonyms	MHC; KRAS; K-Ras 2; KRAS2; C-K-RAS; CFC2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; KRAS1; KRAS2; NS; NS3; RASK2; GTPase Kras; KI-RAS; RALD
MHC Form	Tetramer
Allele	HLA-A*11:01
Accession	AAV53343.1(HLA-A*11:01)&P61769(B2M)&VVGAVGVGK
Species	Human
Biotinylated	no
Amino Acid Range	Gly25-Thr305(HLA-A*11:01), Ile21-Met119(B2M) and VVGAVGVGK peptide
Molecular Weight	The protein has a predicted MW of 35.36 kDa (HLA-A*11:01) and 11.9 kDa (B2M) same as Bis-Tris PAGE result.
Product Tag	C-His-Avi
Fluorophore	FITC-Labeled
Expression System	E.coli
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in 20mM Tris, 200mM NaCl (pH 8.0).
Stability And Storage	Valid for 6 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	FITC-Labeled Human HLA-A*11:01&B2M&KRAS G12V (VVGAVGVGK) Tetramer on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of FITC-Labeled Human HLA-A*11:01&B2M&KRAS G12V (VVGAVGVGK) Tetramer is greater than 95% as determined by SEC-HPLC.

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