Product Description |
Recombinant FITC-Labeled Human Transferrin Protein is expressed from HEK293 with His tag at the C-terminus.It contains Val20-Pro698. |
Product Background |
Transferrin (Tf), an iron transporter, is mainly biosynthesized in the liver, but can also be biosynthesized in the brain; i.e., by oligodendrocytes and the choroid plexus, a cerebrospinal fluid (CSF) producing tissue. The CSF contains two Tf isoforms, brain-type Tf and serum-type Tf, which differ in their glycan structures. Brain-type Tf is uniquely glycolsylated with biantennary asialo- and agalacto-complex type N-glycans that carry bisecting β1,4-GlcNAc and core α1,6-Fuc. The glycans of serum-type Tf in the CSF are similar to those of Tf in serum. |
Product Category |
Recombinant Protein |
Target |
Transferrin |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Val20-Pro698 |
Molecular Weight |
The protein has a predicted MW of 76.3 kDa. Due to glycosylation, the protein migrates to 78-88 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Fluorophore |
FITC |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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