Name: Human 4-1BB CDR123 Protein (BB4-HM213)
Brand: KactusBio
SKU: BB4-HM213-100UG
Price: 396.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-hFc (IgG1)
Purity: > 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Activity: Immobilized Human 4-1BB Ligand (Trimer), His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human 4-1BB CDR123, hFc Tag with the EC50 of 1.3ng/ml determined by ELISA.
Amino Acid Range: Leu24-Lys118

Catalog #BB4-HM213

Size

100UG

500UG

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Human 4-1BB CDR123 Protein (BB4-HM213) Summary

Product Description	Recombinant Human 4-1BB CDR123 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Leu24-Lys118.
Product Background	4-1BB, is also known as CD137, is a type 2 transmembrane glycoprotein receptor belonging to the TNF superfamily.CD137 can be expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, CD137 expression is found on dendritic cells, B cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation.
Product Category	Recombinant Protein / Antibody discovery / Immune checkpoint proteins

Human 4-1BB CDR123 Protein (BB4-HM213) Specifications/Details

Protein	4-1BB/TNFRSF9
Synonyms	CD137; TNFRSF9; 4-1BB ligand receptor; 41BB; 4-1BB; CDw137; FLJ43501; ILA; T cell antigen ILA
Accession	Q07011-1
Species	Human
Biotinylated	no
Amino Acid Range	Leu24-Lys118
Molecular Weight	The protein has a predicted MW of 36.8 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human 4-1BB Ligand (Trimer), His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human 4-1BB CDR123, hFc Tag with the EC50 of 1.3ng/ml determined by ELISA.
Product Tag	C-hFc (IgG1)
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22um filtered solution in PBS, 8% trehalose (pH 7.4).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human 4-1BB Ligand (Trimer), His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human 4-1BB CDR123, hFc Tag with the EC50 of 1.3ng/ml determined by ELISA.
	Human 4-1BB CDR123 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human 4-1BB CDR123 is greater than 90% as determined by SEC-HPLC.

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