Human 4-1BB Ligand/TNFSF9 Trimer Protein (BBL-HM141)
Catalog: BBL-HM141
Order now get it on
Product Description | Recombinant Human 4-1BB Ligand/TNFSF9 Trimer Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Arg71-Glu254. |
Product Background |
The 4-1BBL is the high affinity ligand of 4-1BB, also known as CD137L or TNFSF9. 4-1BB ligand (4-1BBL) is an inducible molecule present on several APC types, including B cells, macrophages and DCs.4-1BB:4-1BBL pathway seems to amplify the existing costimulatory signals, even if the engagement of 4-1BB in the presence of a strong TCR signaling can induce IL-2 production in a CD28-independent manner. |
Product Category |
Recombinant Protein |
Target |
4-1BB Ligand/TNFSF9 Trimer |
Synonyms | 41BB Ligand; 4-1BB Ligand; 4-1BBL; CD137L; TNFSF9 |
Accession | |
Species |
Human |
Amino Acid Range |
Arg71-Glu254 |
Molecular Weight | The protein has a predicted MW of 61.8 kDa same as Tris-Bis PAGE result. |
Activity |
Immobilized Human 4-1BB Ligand Trimer, His Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Human 4-1BB, hFc Tag with the EC50 of 13.7ng/ml determined by ELISA. See testing image for detail. |
Product Tag |
N-His |
Express System |
HEK293 |
Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
Endotoxin | Less than 1EU per ug by the LAL method. |
Form | Lyophilized |
Shipping | Shipped at ambient temperature. |
Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
You may also be interested in
View more associated products