Human 4-1BB Ligand/TNFSF9 Trimer Protein (BBL-HM241)
Human 4-1BB Ligand/TNFSF9 Trimer Protein (BBL-HM241)
Human 4-1BB Ligand/TNFSF9 Trimer Protein (BBL-HM241)
  • Express System: HEK293
  • Product Tag: N-monomeric hFc
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Activity: Immobilized Human 4-1BB, His Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Human 4-1BB Ligand Trimer, hFc Tag with the EC50 of 5.4ng/ml determined by ELISA (QC Test). See testing image for detail.
  • Amino Acid Range: Arg71-Glu254
Catalog #BBL-HM241
Regular price $315.00
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Product Description

Recombinant Human 4-1BB Ligand/TNFSF9 Trimer Protein is expressed from HEK293 with monomeric hFc tag at the N-Terminus.It contains Arg71-Glu254.

Product Background

The 4-1BBL is the high affinity ligand of 4-1BB, also known as CD137L or TNFSF9. 4-1BB ligand (4-1BBL) is an inducible molecule present on several APC types, including B cells, macrophages and DCs.4-1BB:4-1BBL pathway seems to amplify the existing costimulatory signals, even if the engagement of 4-1BB in the presence of a strong TCR signaling can induce IL-2 production in a CD28-independent manner.

Product Category

Recombinant Protein / Antibody discovery / Immune checkpoint proteins

Protein

4-1BB Ligand/TNFSF9 Trimer

Synonyms

41BB Ligand; 4-1BB Ligand; 4-1BBL; CD137L; TNFSF9

Accession

Species

Human

Biotinylated

no

Amino Acid Range

Arg71-Glu254

Molecular Weight

The protein has a predicted MW of 84.3 kDa same as Bis-Tris PAGE result.

Activity

Immobilized Human 4-1BB, His Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Human 4-1BB Ligand Trimer, hFc Tag with the EC50 of 5.4ng/ml determined by ELISA (QC Test). See testing image for detail.

Product Tag

N-monomeric hFc

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human 4-1BB, His Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Human 4-1BB Ligand Trimer, hFc Tag with the EC50 of 5.4ng/ml determined by ELISA (QC Test). Immobilized Human 4-1BB, His Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Human 4-1BB Ligand Trimer, hFc Tag with the EC50 of 5.4ng/ml determined by ELISA (QC Test).
Human 4-1BB Ligand (Trimer) on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human 4-1BB Ligand (Trimer) on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human 4-1BB Ligand (Trimer) is greater than 95% as determined by SEC-HPLC. The purity of Human 4-1BB Ligand (Trimer) is greater than 95% as determined by SEC-HPLC.

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