Name: Human 4-1BB/TNFRSF9 Protein (BB4-HM241)
Brand: KactusBio
SKU: BB4-HM241-100UG
Price: 270.0 USD
Availability: InStock

Catalog #BB4-HM241

Size

100UG

500UG

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Human 4-1BB/TNFRSF9 Protein (BB4-HM241) Summary

Product Description	Recombinant Human 4-1BB/TNFRSF9 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-terminus.It contains Asp119-Gly159.
Product Background	4-1BB, is also known as CD137, is a type 2 transmembrane glycoprotein receptor belonging to the TNF superfamily.CD137 can be expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, CD137 expression is found on dendritic cells, B cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation.
Product Category	Recombinant Protein / Antibody discovery / Immune checkpoint proteins

Human 4-1BB/TNFRSF9 Protein (BB4-HM241) Specifications/Details

Protein	4-1BB/TNFRSF9
Synonyms	CD137; TNFRSF9; 4-1BB ligand receptor; 41BB; 4-1BB; CDw137; FLJ43501; ILA; T cell antigen ILA
Accession	Q07011
Species	Human
Biotinylated	no
Amino Acid Range	Asp119-Gly159
Molecular Weight	The protein has a predicted MW of 30.46 kDa. Due to glycosylation, the protein migrates to 52-65 kDa based on Bis-Tris PAGE result.
Product Tag	C-hFc (IgG1)
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human 4-1BB on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human 4-1BB is greater than 95% as determined by SEC-HPLC.

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