Name: Human ADAM8 Protein (ADM-HM108)
Brand: KactusBio
SKU: ADM-HM108-100UG
Price: 300.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human ADAM8, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-ADAM8 Antibody, hFc Tag with the EC50 of 8.1ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Ile17-Pro655

Catalog #ADM-HM108

Size

100UG

500UG

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Product Description	Recombinant Human ADAM8 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ile17-Pro655.
Product Background	A Disintegrin And Metalloproteinase (ADAM) proteases constitute a family of multifunctional, membrane-bound proteins with traditional sheddase functions. Their protumorigenic potential has been attributed to both, essential (ADAM10 and ADAM17) and 'dispensable' ADAM proteases (ADAM8, 9, 12, 15, and 19). Of specific interest in this review is the ADAM proteinase ADAM8 that has been identified as a significant player in aggressive malignancies including breast, pancreatic, and brain cancer.
Product Category	Recombinant Protein / Antibody discovery

Protein	ADAM8
Synonyms	ADAM 8; Ms2; Adam8; CD156a; MGC134985
Accession	P78325
Species	Human
Biotinylated	no
Amino Acid Range	Ile17-Pro655
Molecular Weight	The protein has a predicted MW of 70.9 kDa. The protein migrates to 55-70 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human ADAM8, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-ADAM8 Antibody, hFc Tag with the EC50 of 8.1ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human ADAM8, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-ADAM8 Antibody, hFc Tag with the EC50 of 8.1ng/ml determined by ELISA.
	Human ADAM8 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human ADAM8 is greater than 95% as determined by SEC-HPLC.