Human ADAM9 Protein (ADM-HM109)
Human ADAM9 Protein (ADM-HM109)
Human ADAM9 Protein (ADM-HM109)
Human ADAM9 Protein (ADM-HM109)
Human ADAM9 Protein (ADM-HM109)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Activity: Immobilized Human ADAM9, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-ADAM9 Antibody, hFc Tag with the EC50 of 1.0ng/ml determined by ELISA. See testing image for detail.Measured by its ability to cleave a fluorogenic peptide substrate Mca-PLAQAV-Dpa-RSSSR-NH2. The specific activity is > 5.0 pmol/min/ug.
  • Amino Acid Range: Ala206-Asp697
Catalog #ADM-HM109
Regular price $330.00
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Size
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Human ADAM9 Protein (ADM-HM109) Summary

Product Description

Recombinant Human ADAM9 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala206-Asp697.

Product Background

A disintegrin and metalloproteinase 9 (ADAM9) is a member of the transmembrane ADAM family. It is expressed in different types of solid cancer and promotes tumor invasiveness. ADAM9 may be a prognostic marker for vestibular schwannomas (VS), and ADAM9 inhibition might have the potential as a systemic approach for the treatment of VS.

Product Category

Recombinant Protein / Antibody discovery / ADC targets

Human ADAM9 Protein (ADM-HM109) Specifications/Details

Protein
ADAM9
Synonyms
ADAM 9; Meltrin-gamma; Mdc9; Mltng; Adam9; Kiaa0021; AU020942; MDC9; mKIAA0021; CORD9; MCMP; MLTNG
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Ala206-Asp697
Molecular Weight
The protein has a predicted MW of 54.39 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Activity
Immobilized Human ADAM9, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-ADAM9 Antibody, hFc Tag with the EC50 of 1.0ng/ml determined by ELISA. See testing image for detail.Measured by its ability to cleave a fluorogenic peptide substrate Mca-PLAQAV-Dpa-RSSSR-NH2. The specific activity is > 5.0 pmol/min/ug.
Product Tag
C-His

Fluorophore

Unconjugated
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE
Endotoxin
Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22um filtered solution in 50mM Tris, 500mM NaCl, 0.005% Brij-35, 20% Glycerol (pH 8.5).
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Immobilized Human ADAM9, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-ADAM9 Antibody, hFc Tag with the EC50 of 1.0ng/ml determined by ELISA. Immobilized Human ADAM9, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-ADAM9 Antibody, hFc Tag with the EC50 of 1.0ng/ml determined by ELISA.
Immobilized Human ADAM9, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Izeltabart, hFc Tag with the EC50 of 3.6ng/ml determined by ELISA. Immobilized Human ADAM9, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Izeltabart, hFc Tag with the EC50 of 3.6ng/ml determined by ELISA.
Human ADAM9 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human ADAM9 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
Other Available Proteins:
Finding available proteins...
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