Human ADAM9 Protein,-Ultra Low Endotoxin (ADM-HM109-UL)

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE
Activity: Immobilized Human ADAM9, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-ADAM9 Antibody, hFc Tag with the EC50 of 1.0ng/ml determined by ELISA. See testing image for detail.Measured by its ability to cleave a fluorogenic peptide substrate Mca-PLAQAV-Dpa-RSSSR-NH2. The specific activity is > 25 pmol/min/ug.
Amino Acid Range: Ala206-Asp697

Catalog #ADM-HM109-UL

Price

$363.00

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Human ADAM9 Protein,-Ultra Low Endotoxin (ADM-HM109-UL) Summary

Product Description	Recombinant Human ADAM9 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala206-Asp697.
Product Background	A disintegrin and metalloproteinase 9 (ADAM9) is a member of the transmembrane ADAM family. It is expressed in different types of solid cancer and promotes tumor invasiveness. ADAM9 may be a prognostic marker for vestibular schwannomas (VS), and ADAM9 inhibition might have the potential as a systemic approach for the treatment of VS.
Product Category	Recombinant Protein / Antibody discovery / ADC targets

Protein	ADAM9
Synonyms	ADAM 9; Meltrin-gamma; Mdc9; Mltng; Adam9; Kiaa0021; AU020942; MDC9; mKIAA0021; CORD9; MCMP; MLTNG
Accession	Q13443-1
Species	Human
Biotinylated	no
Amino Acid Range	Ala206-Asp697
Molecular Weight	The protein has a predicted MW of 54.39 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human ADAM9, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-ADAM9 Antibody, hFc Tag with the EC50 of 1.0ng/ml determined by ELISA. See testing image for detail.Measured by its ability to cleave a fluorogenic peptide substrate Mca-PLAQAV-Dpa-RSSSR-NH2. The specific activity is > 25 pmol/min/ug.
Product Tag	C-His
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 0.01 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in 20mM NaAc, 150mM NaCl, 0.01% Brij-35, 8% trehalose (pH 5.0).
Reconstitution	Dissolve the lyophilized protein in 20mM NaAc (pH 5.0). It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human ADAM9, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-ADAM9 Antibody, hFc Tag with the EC50 of 1.0ng/ml determined by ELISA.
	Immobilized Human ADAM9, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Izeltabart, hFc Tag with the EC50 of 3.6ng/ml determined by ELISA.
	Human ADAM9 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

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