Name: Human HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer Protein (MHC-HM432T)
Brand: KactusBio
SKU: MHC-HM432T-100UG
Price: 825.0 USD
Availability: InStock

Human HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer Protein (MHC-HM432T)

Human HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer on Bis-Tris PAGE under Non reducing (N) condition. The purity is greater than 95%.

The purity of Human HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His-Avi
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Amino Acid Range: Gly25-Thr305(HLA-A*02:03), Ile21-Met119(B2M) and FMNKFIYEI peptide

Catalog #MHC-HM432T

Size

100UG

500UG

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Product Description	Recombinant Human HLA-A02:03&B2M&AFP (FMNKFIYEI) Tetramer Protein is expressed from HEK293 His tag and Avi tag at the C-Terminus, tetramer is assembled by biotinylated monomer and streptavidin.It contains Gly25-Thr305(HLA-A02:03), Ile21-Met119(B2M) and FMNKFIYEI peptide.
Product Background	Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
Product Category	Recombinant Protein / Antibody discovery / MHC

Protein	HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer
Synonyms	Alpha-fetoprotein; Alpha-1-fetoprotein; Alpha-feto; AFP; HPAFP; AFPD; FETA; MHC
MHC Form	Tetramer
Allele	HLA-A*02:03
Accession	AAA03604.1(HLA-A*02:03)&P61769(B2M)&FMNKFIYEI
Species	Human
Biotinylated	no
Amino Acid Range	Gly25-Thr305(HLA-A*02:03), Ile21-Met119(B2M) and FMNKFIYEI peptide
Molecular Weight	The protein has a predicted MW of 258 kDa. Due to glycosylation, the protein migrates to 260-265 kDa under Non reducing (N) condition based on Bis-Tris PAGE result.
Product Tag	C-His-Avi
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer on Bis-Tris PAGE under Non reducing (N) condition. The purity is greater than 95%.
	The purity of Human HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer is greater than 95% as determined by SEC-HPLC.