Name: Human AGER Protein (AER-HM101)
Brand: KactusBio
SKU: AER-HM101-100UG
Price: 297.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: The affinity constant of 0.19 uM as determined in SPR assay (Biacore T200).
Amino Acid Range: Ala23- Ala344

Catalog #AER-HM101

Size

100UG

500UG

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Human AGER Protein (AER-HM101) Summary

Product Description	Recombinant Human AGER Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala23- Ala344.
Product Background	The receptor for advanced glycation end products (AGER) is an oncogenic transmembranous receptor up-regulated in various human cancers. AGER promotes proliferation, migration, and inhibits apoptosis of squamous cervical cancer and might function as a tumor promoter in cervical cancer. Our study provides novel evidence for a potential role of AGER in bridging human papillomavirus (HPV)-induced inflammation and cervical cancer.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Human AGER Protein (AER-HM101) Specifications/Details

Protein	AGER
Synonyms	AGER; RAGE; SCARJ1
Accession	Q15109-1
Species	Human
Biotinylated	no
Amino Acid Range	Ala23- Ala344
Molecular Weight	The protein has a predicted MW of 35.3 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Bis-Tris PAGE result.
Activity	The affinity constant of 0.19 uM as determined in SPR assay (Biacore T200).
Product Tag	C-His
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human AGER, His Tag immobilized on CM5 Chip can bind Human HMGB1, His Tag with an affinity constant of 0.19 uM as determined in SPR assay (Biacore T200).
	Human AGER on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human AGER is greater than 95% as determined by SEC-HPLC.

Other Available Proteins:

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