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Human Alpha Synuclein (A53T) Protein (ALS-HE002) Summary
Product Description |
Recombinant Human Alpha Synuclein (A53T) Protein is expressed from E.coli without tag.It contains Met1-Ala140 (A53T). |
Product Background |
Alpha-synuclein (α-synuclein) is a protein that is abundantly found in the brain and in a lesser amount in the heart and muscles. Its overexpression in the neurons leads to the formation of Lewy bodies that damage the dopaminergic neurons in the subtantianigra of the midbrain and leads to the progression of Parkinson's Disease (PD). |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery/Others |
Human Alpha Synuclein (A53T) Protein (ALS-HE002) Specifications/Details
Protein |
Alpha Synuclein |
Synonyms |
Alpha-synuclein; NACP; SNCA; NACP; PARK1; |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Met1-Ala140(A53T) |
Molecular Weight |
The protein has a predicted MW of 14.49 kDa same as Bis-Tris PAGE result. |
Product Tag |
No Tag |
Fluorophore |
Unconjugated |
Expression System |
E.coli |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
|
|
Human Alpha Synuclein (A53T) on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
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The purity of Human Alpha Synuclein (A53T) is greater than 95% as determined by SEC-HPLC. |
Other Available Proteins:
Finding available proteins...
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