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Human Alpha Synuclein Protein (ALS-HE001) Summary
Product Description |
Recombinant Human Alpha Synuclein Protein is expressed from E.coli without tag.It contains Met1-Ala140. |
Product Background |
Alpha-synuclein (α-synuclein) is a small, acidic protein containing 140 amino acids, highly expressed in the brain and primarily localized in the presynaptic terminals. It is found in high concentrations in Lewy Bodies, proteinaceous aggregates that constitute a typical histopathologic hallmark of Parkinson's disease. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery | Others |
Human Alpha Synuclein Protein (ALS-HE001) Specifications/Details
Protein |
Alpha Synuclein |
Synonyms |
Alpha-synuclein; NACP; SNCA; PARK1 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Met1-Ala140 |
Molecular Weight |
The protein has a predicted MW of 14.5 kDa same as Bis-Tris PAGE result. |
Product Tag |
No Tag |
Fluorophore |
Unconjugated |
Expression System |
E.coli |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in 20mM Tris, 150mM NaCl (pH 8.0). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
|
|
Human Alpha Synuclein on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
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The purity of Human Alpha Synuclein is greater than 95% as determined by SEC-HPLC. |
Other Available Proteins:
Finding available proteins...
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