Human Amyloid Beta 42/Abeta 42 Protein (AMB-HE042)

Immobilized Human Amyloid Beta 42, No Tag at 1ug/ml(100ul/well) on the plate. Dose response curve for Trontinemab, hFc Tag with the EC50 of 41.3ng/ml determined by ELISA.

Human Amyloid Beta 42 (HFIP treated) on Bis-Tris PAGE under reduced condition. The purity is greater than 90%.

The purity of Human Amyloid Beta 42 is greater than 90% as determined by SEC-HPLC.

Express System: E.coli
Product Tag: No Tag
Purity: > 90% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Activity: Immobilized Human Amyloid Beta 42, No Tag at 1ug/ml(100ul/well) on the plate. Dose response curve for Trontinemab, hFc Tag with the EC50 of 41.3ng/ml determined by ELISA.
Amino Acid Range: Asp672-Ala713

Catalog #AMB-HE042

Price

$525⁰⁰

Size

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Human Amyloid Beta 42/Abeta 42 Protein (AMB-HE042) Summary

Product Description

Recombinant Human Amyloid Beta 42/Abeta 42 Protein is expressed from E.coli without tag.It contains Asp672-Ala713.

Product Background

Multiple lines of evidence indicate that the amyloid β peptide (Aβ) plays an important role in the pathogenesis of Alzheimer's disease. In nature, Aβ does not occur as a single molecular species, an more than 20 different Aβ sequences have been detected in human cerebrospinal ﬂuid an brain. The most common Aβ isoform is Aβ1–40, a 40-residue peptide that begins at Asp1 an terminates a Val40. Increased production of Aβ1–42, a peptide that differs from Aβ1–40 by addition of Ile and Ala to the C-terminus, is particularly associated with disease.

Human Amyloid Beta 42/Abeta 42 Protein (AMB-HE042) Specifications/Details

Protein	Amyloid Beta 42/Abeta 42
Synonyms	Amyloid-beta protein 42; Abeta42; Beta-APP42; Aβ42;Ab42; A beta 42
Accession	P05067-1
Species	Human
Biotinylated	no
Amino Acid Range	Asp672-Ala713
Molecular Weight	The protein has a predicted MW of 4.51 kDa same as Bis-Tris PAGE result.
Activity	Immobilized Human Amyloid Beta 42, No Tag at 1ug/ml(100ul/well) on the plate. Dose response curve for Trontinemab, hFc Tag with the EC50 of 41.3ng/ml determined by ELISA.
Product Tag	No Tag
Expression System	E.coli
Purity	> 90% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in 10 mM NaOH.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Immobilized Human Amyloid Beta 42, No Tag at 1ug/ml(100ul/well) on the plate. Dose response curve for Trontinemab, hFc Tag with the EC50 of 41.3ng/ml determined by ELISA.
	Human Amyloid Beta 42 (HFIP treated) on Bis-Tris PAGE under reduced condition. The purity is greater than 90%.
	The purity of Human Amyloid Beta 42 is greater than 90% as determined by SEC-HPLC.