Human ANGPTL2/Angiopoietin-like 2 Protein (ANG-HM4L2)
Human ANGPTL2/Angiopoietin-like 2 Protein (ANG-HM4L2)
  • Express System: HEK293
  • Product Tag: C-His-Avi
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: The affinity constant of 0.22 uM as determined in SPR assay (Biacore T200). See testing image for detail.
  • Amino Acid Range: Thr260-His493
Catalog #ANG-HM4L2
Regular price $225.00
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Product Description

Recombinant Human ANGPTL2/Angiopoietin-like 2 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Thr260-His493.

Product Background

Angiopoietin-like 2 (ANGPTL2) is a proinflammatory protein belonging to the angiopoietin-like family. ANGPTL2 is secreted and detected in the systemic circulation. Different observational clinical studies reported that circulating levels of ANGPTL2 increase significantly in various chronic inflammatory diseases and showed associations between ANGPTL2 levels and diagnosis and/or prognosis of cardiovascular diseases, diabetes, chronic kidney disease, and various types of cancers.

Product Category

Recombinant Protein / Antibody discovery

Protein

ANGPTL2/Angiopoietin-like 2

Synonyms

ARP2; HARP; angiopoietin-like 2; ANGPTL2; ANGRP2; MGC8889

Accession

Species

Human

Biotinylated

no

Amino Acid Range

Thr260-His493

Molecular Weight

The protein has a predicted MW of 30.1 kDa. Due to glycosylation, the protein migrates to 31-35 kDa based on Bis-Tris PAGE result.

Activity

The affinity constant of 0.22 uM as determined in SPR assay (Biacore T200). See testing image for detail.

Product Tag

C-His-Avi

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS, 200mM L-arginine (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human LILRB2, hFc Tag captured on CM5 Chip via Protein A can bind Human ANGPTL2, His Tag with an affinity constant of 0.22 uM as determined in SPR assay (Biacore T200). Human LILRB2, hFc Tag captured on CM5 Chip via Protein A can bind Human ANGPTL2, His Tag with an affinity constant of 0.22 uM as determined in SPR assay (Biacore T200).
Human ANGPTL2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human ANGPTL2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human ANGPTL2 is greater than 95% as determined by SEC-HPLC. The purity of Human ANGPTL2 is greater than 95% as determined by SEC-HPLC.

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