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Human Azurocidin/CAP37/AZU1/HBP Protein, Ultra Low Endotoxin (HBP-HM101-UL) Summary
Product Description |
Recombinant Human Azurocidin/CAP37/AZU1 /HBP Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ile27-Pro250. |
Product Background |
Heparin-binding protein (HBP), also known as cationic antimicrobial protein 37 (CAP37) and Azurocidin, is a member of the serine protease family that includes Cathepsin G, neutrophil elastase (NE), and proteinase 3 (PR3). This is a neutrophil granule-derived antibacterial and monocyte- and fibroblast-specific chemotactic glycoprotein. Binds heparin. The cytotoxic action is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery | Others |
Human Azurocidin/CAP37/AZU1/HBP Protein, Ultra Low Endotoxin (HBP-HM101-UL) Specifications/Details
Protein |
Azurocidin/CAP37/AZU1/HBP |
Synonyms |
CAP37; AZU; AZU1; Azurocidin; HBP; AZAMP; HUMAZUR; NAZC; azurocidin 1 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Ile27-Pro250 |
Molecular Weight |
The protein has a predicted MW of 25.3 kDa. Due to glycosylation, the protein migrates to 35-45 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Fluorophore |
Unconjugated |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 0.01 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22 um filtered solution in 20mM PB, 500mM NaCl (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
|
|
Human Azurocidin on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
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The purity of Human Azurocidin is greater than 95% as determined by SEC-HPLC. |
Other Available Proteins:
Finding available proteins...
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