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Human BAFFR/TNFRSF13C Protein (BAF-HM60R) Summary
Product Description |
Recombinant Human BAFFR/TNFRSF13C Protein is expressed from HEK293 with Llama IgG2b Fc tag at the C-terminus.It contains Ser7-Ala71. |
Product Background |
BAFFR is an atypical representative of the TNF-receptor super-family. BAFFR [BAFFR = B cell activating f actor of the TNF-f amily receptor; a.k.a. BR3, Bcmd] expression starts when the immature B cells develop to transitional B cells, which then receive BAFFR-dependent pro-survival signals to rescue them from premature cell death. At protein level, the BAFFR is expressed on the surface of all human peripheral B cell subsets except for plasma cells and for centroblasts located in the dark zone of germinal centers. Its expression is upregulated after the expression of functional B cell antigen receptors (BCR) in response to tonic BCR signaling, which enhances BAFFR expression by immature and transitional B cells |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery/Others |
Human BAFFR/TNFRSF13C Protein (BAF-HM60R) Specifications/Details
Protein |
BAFFR/TNFRSF13C |
Synonyms |
CD268; BAFFR; BR3; TNFRSF13C; BROMIX; CVID4; prolixin |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Ser7-Ala71 |
Molecular Weight |
The protein has a predicted MW of 33.85 kDa. Due to glycosylation, the protein migrates to 45-65 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Human BAFF (Trimer), His Tag (Cat.BAF-HM112) at 5ug/ml (100ul/well) on the plate. Dose response curve for Human BAFFR, Llama Fc Tag with the EC50 of 0.14ug/ml determined by ELISA. |
Product Tag |
C-Llama IgG2b Fc |
Fluorophore |
Unconjugated |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
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Immobilized Human BAFF (Trimer), His Tag (Cat.BAF-HM112) at 5ug/ml (100ul/well) on the plate. Dose response curve for Human BAFFR, Llama Fc Tag with the EC50 of 0.14ug/ml determined by ELISA. |
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Human BAFFR on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
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The purity of Human BAFFR is greater than 90% as determined by SEC-HPLC. |
Other Available Proteins:
Finding available proteins...
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