Human BCAM Protein (BCA-HM10M)
Human BCAM Protein (BCA-HM10M)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Glu32-Ala547
Catalog #BCA-HM10M
Regular price $240.00
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Product Description
Recombinant Human BCAM Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu32-Ala547.
Product Background
Lutheran/basal cell adhesion molecule (Lu/BCAM) is a transmembrane adhesion molecule expressed by erythrocytes and endothelial cells that can interact with the extracellular matrix protein laminin-α5. In sickle cell disease, Lu/BCAM is thought to contribute to adhesion of sickle erythrocytes to the vascular wall, especially during vaso-occlusive crises.
Product Category
Recombinant Protein
Target
BCAM
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Glu32-Ala547
Molecular Weight
The protein has a predicted MW of 57.32 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Bis-Tris PAGE result.
Product Tag
C-His
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Human BCAM on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human BCAM is greater than 95% as determined by SEC-HPLC.

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