Human BCAM Protein (BCA-HM10M)
Human BCAM Protein (BCA-HM10M)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Glu32-Ala547
Catalog #BCA-HM10M
Regular price $264.00
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Product Description

Recombinant Human BCAM Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu32-Ala547.

Product Background

Lutheran/basal cell adhesion molecule (Lu/BCAM) is a transmembrane adhesion molecule expressed by erythrocytes and endothelial cells that can interact with the extracellular matrix protein laminin-α5. In sickle cell disease, Lu/BCAM is thought to contribute to adhesion of sickle erythrocytes to the vascular wall, especially during vaso-occlusive crises.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others
Protein
BCAM
Synonyms
LU; MSK19; Gplu; CD239; Lutheran;
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Glu32-Ala547
Molecular Weight
The protein has a predicted MW of 57.32 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Bis-Tris PAGE result.

Product Tag

C-His
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human BCAM on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human BCAM on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human BCAM is greater than 95% as determined by SEC-HPLC. The purity of Human BCAM is greater than 95% as determined by SEC-HPLC.
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