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Human BCMA/TNFRSF17 (P33S) Protein (BCM-HM1D2) Summary
Product Description |
Recombinant Human BCMA/TNFRSF17 (P33S) Protein is expressed from HEK293 with His tag at the C-terminus.It contains Met1-Ala54 (P33S). |
Product Background |
B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene. TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF). |
Product Category |
Recombinant Protein / Antibody discovery / CAR-T targets, ADC targets |
Human BCMA/TNFRSF17 (P33S) Protein (BCM-HM1D2) Specifications/Details
Protein |
BCMA/TNFRSF17 |
Synonyms |
CD269; TNFRSF17; BCMA; BCM; TNFRSF13A |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Met1-Ala54 (P33S) |
Molecular Weight |
The protein has a predicted MW of 7.5 kDa. Due to glycosylation, the protein migrates to 15-20 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Human BCMA (P33S), His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human BAFF, hFc Tag with the EC50 of 4.1ng/ml determined by ELISA. |
Product Tag |
C-His |
Fluorophore |
Unconjugated |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 0.1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
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Immobilized Human BCMA (P33S), His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human BAFF, hFc Tag with the EC50 of 4.1ng/ml determined by ELISA. |
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Immobilized Human BCMA (P33S), His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human APRIL (Trimer), His Avi Tag with the EC50 of 19.6ng/ml determined by ELISA. |
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Immobilized Human BCMA (P33S), His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-BCMA Antibody, hFc Tag with the EC50 of 3.5ng/ml determined by ELISA. |
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Human BCMA (P33S) on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
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The purity of Human BCMA (P33S) is greater than 95% as determined by SEC-HPLC. |
Other Available Proteins:
Finding available proteins...
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