Human BMP10 Protein (BMP-HM010)

Express System: HEK293
Product Tag: No Tag
Purity: > 95% as determined by Bis-Tris PAGE
Amino Acid Range: Ala317-Arg424

Catalog #BMP-HM010

Price

$600⁰⁰

Size

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Human BMP10 Protein (BMP-HM010) Summary

Product Description

Recombinant Human BMP10 Protein is expressed from HEK293 without tag.It contains Ala317-Arg424.

Product Background

Bone morphogenetic protein 10 (BMP10) is a cardiac peptide growth factor belonging to the transforming growth factor β superfamily that critically controls cardiovascular development, growth, and maturation. It has been shown that BMP10 elicits its intracellular signaling through a receptor complex of activin receptor-like kinase 1 with morphogenetic protein receptor type II or activin receptor type 2A.

Human BMP10 Protein (BMP-HM010) Specifications/Details

Protein	BMP10
Synonyms	BMP-10;BMP10;Bone morphogenetic protein-10; Bone morphogenetic protein 10
Accession	O95393
Species	Human
Biotinylated	no
Amino Acid Range	Ala317-Arg424
Molecular Weight	The protein has a predicted MW of 12.16 kDa. Due to glycosylation, the protein migrates to 13-15 kDa based on Bis-Tris PAGE result.
Product Tag	No Tag
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 0.1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in 4mM HCI.
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Human BMP10 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	Measured by its ability to induce Alkaline Phosphatase production by ATDC5 mouse chondrogenic cells. The ED50-for this effect is 10-60 ng/mL.