Product Description |
Recombinant Human BSPII Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe17-Gln317. |
Product Background |
IBSP (Integrin Binding Sialoprotein) is a Protein Coding gene. Diseases associated with IBSP include Fibrous Dysplasia and Chondromalacia. Among its related pathways are Degradation of the extracellular matrix and Cytoskeletal Signaling.The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. |
Product Category |
Recombinant Protein |
Target |
BSPII |
Synonyms |
BNSP; BSP 2; BSP II; BSP; BSP-II; IBSP; SP II; SPII; SP-II |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Phe17-Gln317 |
Molecular Weight |
The protein has a predicted MW of 34.3 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Human BSPII on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Human BSPII is greater than 95% as determined by SEC-HPLC. |
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